Announcements Trials
Browse Landscape

Phase

Phase 2/3 2Phase 2 2Phase 1/2 2

Status

Active not recruiting 3Recruiting 2Terminated 1

Sponsor Class

INDUSTRY 3OTHER 2NIH 1

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 6Plasma cell 1Other hematologic neoplasm 1Myeloid 1Head & Neck 1Gynecologic 1Gastrointestinal 1Endocrine 1Dermatologic 1CNS 1

Conditions

Melanoma 7Carcinoma, Non-Small-Cell Lung 6Neoplasms 5Multiple Myeloma 3Thyroid Carcinoma, Anaplastic 2Thyroid Cancer, Papillary 2Pancreatic Neoplasms 2Ovarian Neoplasms 2Neoplasms by Site 2Neoplasms by Histologic Type 2Lymphoma, Non-Hodgkin 2Lung Neoplasms 2Hematologic Neoplasms 2Erdheim-Chester Disease 2Xanthogranuloma, Juvenile 1Thyroid Neoplasms 1Skin Neoplasms 1Sarcoma 1Pancreatic Adenocarcinoma 1Neoplasms, Unknown Primary 1Microsatellite Unstable Colorectal Cancer 1Lymphoproliferative Disorders 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Acute 1Laryngeal Neoplasms 1Inflammatory Breast Neoplasms 1Histiocytosis, Sinus 1Histiocytosis, Langerhans-Cell 1Histiocytic Sarcoma 1Histiocytic Disorders, Malignant 1

Interventions

pembrolizumab 243Carboplatin 211Pemetrexed 177Cisplatin 131Paclitaxel 113Nivolumab 101Docetaxel 87osimertinib 85durvalumab 78Specimen Handling 56atezolizumab 55Gemcitabine 52Drug Therapy 52Magnetic Resonance Spectroscopy 50Radiosurgery 48Radiotherapy 47Ipilimumab 41130-nm albumin-bound paclitaxel 39cemiplimab 38Bevacizumab 34Cetuximab 30tislelizumab 29amivantamab 22Taxes 22Platinum Compounds 20Blood Specimen Collection 20Immunotherapy 18Immune Checkpoint Inhibitors 18Radiation 17Erlotinib Hydrochloride 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Carcinoma, Non-Small-Cell Lung × cobimetinib × 1 year × Clear all
NCT03178552 2026-06-05

B-FAST

Hoffmann-La Roche

Phase 2/3 Active not recruiting
1,000 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04302025 2026-05-22

NAUTIKA1

Genentech, Inc.

Phase 2 Recruiting
99 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03337698 2026-05-12

Morpheus Lung

Hoffmann-La Roche

Phase 1/2 Terminated
314 enrolled 31 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03202940 2026-05-08

A Phase IB/II Study of Alectinib Combined With Cobimetinib in Advanced ALK-Rearranged (ALK+) NSCLC

Massachusetts General Hospital

Phase 1/2 Active not recruiting
16 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT03600701 2025-10-07

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 2 Active not recruiting
51 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

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