Announcements Trials
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Phase

Phase 2 5

Status

Terminated 3Unknown 1Completed 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 5

Conditions

Polycystic Ovary Syndrome 14Breast Neoplasms 11Prostatic Neoplasms 9Obesity 7Insulin Resistance 6Carcinoma, Non-Small-Cell Lung 5Lung Neoplasms 4Colorectal Neoplasms 4Motor Activity 3Adenocarcinoma of Lung 3Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Neoplasms 2Menstruation Disturbances 2Lymphoma, Large B-Cell, Diffuse 2Head and Neck Neoplasms 2Endometrial Neoplasms 2Diabetes Mellitus 2Weight Loss 1Urothelial Cancer 1Thyroid Diseases 1Thoracic Neoplasms 1Smoldering Multiple Myeloma 1Rectal Neoplasms 1Prediabetic State 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pleural Effusion, Malignant 1Overweight 1Ovarian, Fallopian Tube, and Primary Peritoneal Cancer 1Non-alcoholic Fatty Liver Disease 1

Interventions

Carboplatin 235Pemetrexed 214Paclitaxel 160Cisplatin 150pembrolizumab 145Erlotinib Hydrochloride 141Docetaxel 133Gemcitabine 94Bevacizumab 85Nivolumab 72Radiotherapy 62atezolizumab 40Radiosurgery 37Afatinib 37osimertinib 35130-nm albumin-bound paclitaxel 35Cetuximab 34durvalumab 33Ipilimumab 32Gefitinib 31Albumin-Bound Paclitaxel 29Vinorelbine 23Taxes 22Etoposide 20Crizotinib 19Radiation 17Sorafenib 16Cyclophosphamide 16Dexamethasone 15Magnetic Resonance Spectroscopy 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Has results × Carcinoma, Non-Small-Cell Lung × Metformin × Clear all
NCT02186847 2026-05-22

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

NRG Oncology

Phase 2 Completed
170 enrolled 19 charts
Thoracic

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung

NCT03048500 2020-10-14

Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Northwestern University

Phase 2 Unknown
17 enrolled 10 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01717482 2020-03-10

Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer

Mayo Clinic

Phase 2 Terminated
6 enrolled 5 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02285855 2020-01-06

Metformin in Non Small Cell Lung Cancer (NSCLC)

M.D. Anderson Cancer Center

Phase 2 Terminated
27 enrolled 11 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01578551 2018-12-19

Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated
25 enrolled 9 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

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