Announcements Trials
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Phase

Phase 2 2Phase 3 1Phase 1/2 1

Status

Completed 4

Sponsor Class

INDUSTRY 2OTHER 1NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Gynecologic 1Endocrine 1

Conditions

Ovarian Neoplasms 26Small Cell Lung Carcinoma 22Neuroblastoma 12Fallopian Tube Neoplasms 12Uterine Cervical Neoplasms 8Carcinoma, Ovarian Epithelial 8Lung Neoplasms 7Neoplasm Metastasis 5Carcinoma, Non-Small-Cell Lung 4Leukemia, Myeloid, Acute 3Ganglioneuroblastoma 3Brain Neoplasms 3Sarcoma 2Recurrence 2Neuroectodermal Tumors, Primitive, Peripheral 2Neoplasms 2Hereditary Sensory and Autonomic Neuropathies 2Gliosarcoma 2Glioblastoma 2Central Nervous System Neoplasms 2Carcinoma, Small Cell 2Carcinoma, Neuroendocrine 2Thrombocythemia, Essential 1Sarcoma, Ewing 1Rhabdoid Tumor 1Retinoblastoma 1Retinal Neoplasms 1Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1

Interventions

Carboplatin 235Pemetrexed 214Paclitaxel 160Cisplatin 150pembrolizumab 145Erlotinib Hydrochloride 141Docetaxel 133Gemcitabine 94Bevacizumab 85Nivolumab 72Radiotherapy 62atezolizumab 40Radiosurgery 37Afatinib 37osimertinib 35130-nm albumin-bound paclitaxel 35Cetuximab 34durvalumab 33Ipilimumab 32Gefitinib 31Albumin-Bound Paclitaxel 29Vinorelbine 23Taxes 22Etoposide 20Crizotinib 19Radiation 17Sorafenib 16Cyclophosphamide 16Dexamethasone 15Magnetic Resonance Spectroscopy 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Has results × Carcinoma, Non-Small-Cell Lung × Topotecan × Clear all
NCT02487095 2025-04-13

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
62 enrolled 29 charts
EndocrineGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Ovarian Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT00065182 2019-06-24

Comparison of IV Topotecan/Docetaxel to Docetaxel Alone in Second-Line Stage IIIB/IV Non-Small Cell Lung Cancer

GlaxoSmithKline

Phase 2 Completed
399 enrolled 12 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00365547 2017-12-28

Topotecan and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Did Not Respond to Previous Systemic Chemotherapy

Masonic Cancer Center, University of Minnesota

Phase 2 Completed
46 enrolled 11 charts
Thoracic

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00390806 2014-01-20

Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer

GlaxoSmithKline

Phase 3 Completed
472 enrolled 35 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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