Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 3 1Phase 1/2 1

Status

Completed 4Terminated 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 4Observational 1

Sponsor

Cancer Type

Thoracic 5Lymphoid 1

Conditions

Carcinoma, Non-Small-Cell Lung 5Lung Neoplasms 4Carcinoma 2ALK-positive Advanced NSCLC 2Neoplasms 1Lymphoma, Large-Cell, Anaplastic 1Carcinoma, Squamous Cell 1Carcinoma, Large Cell 1Brain Neoplasms 1Adenocarcinoma 1ALK-positive NSCLC 1ALK+ Advanced NSCLC 1

Interventions

Carboplatin 235Pemetrexed 214Paclitaxel 160Cisplatin 150pembrolizumab 145Erlotinib Hydrochloride 141Docetaxel 133Gemcitabine 94Bevacizumab 85Nivolumab 72Radiotherapy 62atezolizumab 40Radiosurgery 37Afatinib 37osimertinib 35130-nm albumin-bound paclitaxel 35Cetuximab 34durvalumab 33Ipilimumab 32Gefitinib 31Albumin-Bound Paclitaxel 29Vinorelbine 23Taxes 22Etoposide 20Crizotinib 19Radiation 17Sorafenib 16Cyclophosphamide 16Dexamethasone 15Magnetic Resonance Spectroscopy 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Has results × Carcinoma, Non-Small-Cell Lung × brigatinib × Clear all
NCT05834348 2025-03-30

DELINOR

Pfizer

Completed
5,279 enrolled 10 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02706626 2023-01-26

Trial of Brigatinib After Treatment With Next-Generation ALK Inhibitors

Criterium, Inc.

Phase 2 Terminated
32 enrolled 9 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02737501 2021-08-20

ALTA-1L

Takeda

Phase 3 Completed
275 enrolled 23 charts 1 FDA
Thoracic

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT01449461 2021-08-17

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral Anaplastic Lymphoma Kinase (ALK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Brigatinib (AP26113)

Takeda

Phase 1/2 Completed
137 enrolled 38 charts
LymphoidThoracic

Carcinoma, Non-Small-Cell Lung, Lymphoma, Large-Cell, Anaplastic

NCT02094573 2021-03-15

A Study to Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib

Takeda

Phase 2 Completed
222 enrolled 23 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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