Clinical Trials

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04083599 2026-06-02

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

350 enrolled

DermatologicGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Colorectal Neoplasms

NCT06875310 2026-06-02

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

630 enrolled

BreastGynecologicThoracic

Carcinoma, Non-Small-Cell Lung

NCT06917079 2026-06-02

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Phase 1 Recruiting

665 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT07046923 2026-06-02

A Study of LY4175408 in Participants With Advanced Cancer

Phase 1 Recruiting

240 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT05312840 2026-06-01

Efficacy and Safety of Conventional and Low-dose Platinum Gemcitabine Combined With Sintilimab With Delayed Administration in First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer

Phase 4 Completed

20 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05633667 2026-06-01

VELOCITY-Lung

192 enrolled

Phase NA Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02194738 2026-05-29

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

8,300 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04092283 2026-05-29

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

660 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04956640 2026-05-29

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

540 enrolled

GastrointestinalGynecologicThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07190248 2026-05-29

KANDLELIT-007

675 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07128199 2026-05-28

REZILIENT4

360 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01993810 2026-05-27

Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer

Phase 3 Completed

330 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05015608 2026-05-27

SACHI

Phase 3 Completed

216 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07100080 2026-05-27

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Phase 2/3 Recruiting

500 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03520686 2026-05-26

Nogapendekin Alfa Inbakicept for Advanced Non-Small Cell Lung Cancer

Phase 3 Terminated

102 enrolled

Phase 1 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT05061550 2026-05-22

NeoCOAST-2

Phase 2 Recruiting

630 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06312137 2026-05-22

TroFuse-019

780 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06564844 2026-05-22

TROPION-Lung12

25 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung

NCT06704724 2026-05-22

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

Phase 1 Terminated

30 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT04015778 2026-05-20

A Exploratory Study of Nivolumab Monotherapy or in Combination With Nab-paclitaxel and Carboplatin in Early Stage NSCLC in China

316 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04768075 2026-05-20

Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC

Phase 3 Completed

60 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06561386 2026-05-20

RELATIVITY1093

1,000 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07365319 2026-05-20

TeLuRide-008

Phase 2/3 Recruiting

750 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05789082 2026-05-18

KRAScendo 170

Phase 1/2 Recruiting

320 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06431633 2026-05-18

ARIAN

129 enrolled

DermatologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Lung Diseases

NCT03645928 2026-05-15

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Phase 2 Terminated

225 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT04380636 2026-05-15

MK-7339-012

870 enrolled

Phase 1 Active not recruiting

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04526691 2026-05-15

Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)

145 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06623422 2026-05-15

INTerpath-009

680 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT06417814 2026-05-14

TROPION-Lung15

744 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT06946797 2026-05-14

CheckMate-1533

76 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02453282 2026-05-12

MYSTIC

1,118 enrolled 40 charts

Phase 1 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT03819465 2026-05-12

MAGELLAN

175 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05351788 2026-05-12

SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung Cancer.

Phase 2 Recruiting

110 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung

NCT07397338 2026-05-12

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

Phase 1/2 Recruiting

370 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT04389632 2026-05-11

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Phase 1 Recruiting

1,006 enrolled

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms

NCT06793215 2026-05-11

Krascendo 2

600 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05870319 2026-05-08

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

376 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03456076 2026-05-05

A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer

257 enrolled 14 charts 1 FDA

Carcinoma, Non-Small-Cell Lung

NCT05012254 2026-05-05

NIVIPI-Brain