Announcements Trials
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Phase

Phase 1 5Phase 2 2

Status

Completed 6Withdrawn 1

Sponsor Class

OTHER 5INDUSTRY 2

Study Type

Interventional 7

Sponsor

Cancer Type

Thoracic 7Gastrointestinal 1Breast 1

Conditions

Breast Neoplasms 22Neoplasm Metastasis 15Carcinoma, Non-Small-Cell Lung 7Glioblastoma 6Colorectal Neoplasms 5Triple Negative Breast Neoplasms 4Recurrence 4Ovarian Neoplasms 4Lymphoma, Mantle-Cell 4Lymphoma, Follicular 4Endometrial Neoplasms 4Brain Neoplasms 4Squamous Cell Carcinoma of Head and Neck 3Prostatic Neoplasms 3Pancreatic Neoplasms 3Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Lung Neoplasms 3Hereditary Sensory and Autonomic Neuropathies 3Head and Neck Neoplasms 3Solid Tumors 2Melanoma 2Lymphoma 2Leukemia, Myeloid, Acute 2Leukemia, Lymphocytic, Chronic, B-Cell 2Esophageal Neoplasms 2Waldenstrom Macroglobulinemia 1Unspecified Adult Solid Tumor, Protocol Specific 1Treatment for Metastatic or Locally Advanced Cervical Cancer 1Tongue Neoplasms 1

Interventions

Carboplatin 784Pemetrexed 607Cisplatin 545Paclitaxel 491pembrolizumab 464Docetaxel 440Gemcitabine 328Erlotinib Hydrochloride 307Radiotherapy 258Nivolumab 244Bevacizumab 233osimertinib 178Drug Therapy 164durvalumab 157atezolizumab 135Gefitinib 134Radiosurgery 133Vinorelbine 111Cetuximab 97130-nm albumin-bound paclitaxel 94Ipilimumab 86Magnetic Resonance Spectroscopy 84Taxes 79Surgical Procedures, Operative 74Afatinib 68Albumin-Bound Paclitaxel 66Specimen Handling 61Etoposide 61Cyclophosphamide 60tislelizumab 59

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Carcinoma, Non-Small-Cell Lung × NVP-BKM120 × Clear all
NCT01971489 2023-04-27

Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors

Roswell Park Cancer Institute

Phase 1 Withdrawn
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01570296 2023-03-29

BKM120

National Cancer Centre, Singapore

Phase 1 Completed
38 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01626209 2020-12-09

A Phase I Study of BKM120 in Adult Chinese Patients With Advanced Solid Tumors

Novartis

Phase 1 Completed
32 enrolled
BreastGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms

NCT02128724 2019-08-01

BKM120

University of Oxford

Phase 1 Completed
21 enrolled 23 charts
Thoracic

Hypoxia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01487265 2019-03-06

Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib

SCRI Development Innovations, LLC

Phase 2 Completed
37 enrolled 10 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01723800 2016-09-20

PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung Cancer

City of Hope Medical Center

Phase 1 Completed
9 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01297491 2016-03-11

BASALT-1

Novartis

Phase 2 Completed
63 enrolled 12 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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