Announcements Trials
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Phase

Phase 1 4Phase 2 2

Status

Completed 6Withdrawn 1

Sponsor Class

OTHER 4INDUSTRY 2

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 6Gastrointestinal 1Breast 1

Conditions

Breast Neoplasms 17Neoplasm Metastasis 8Carcinoma, Non-Small-Cell Lung 6Glioblastoma 5Triple Negative Breast Neoplasms 4Lymphoma, Mantle-Cell 4Lymphoma, Follicular 4Colorectal Neoplasms 4Recurrence 3Pancreatic Neoplasms 3Ovarian Neoplasms 3Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Squamous Cell Carcinoma of Head and Neck 2Solid Tumors 2Lymphoma 2Lung Neoplasms 2Leukemia, Myeloid, Acute 2Hereditary Sensory and Autonomic Neuropathies 2Head and Neck Neoplasms 2Endometrial Neoplasms 2Brain Neoplasms 2Waldenstrom Macroglobulinemia 1Unspecified Adult Solid Tumor, Protocol Specific 1Tongue Neoplasms 1Thymoma 1Stomach Neoplasms 1Salivary Gland Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pre-menopausal Breast Cancer 1

Interventions

Carboplatin 341Paclitaxel 262Cisplatin 233Pemetrexed 226Docetaxel 206Erlotinib Hydrochloride 193Gemcitabine 178pembrolizumab 137Bevacizumab 121Radiotherapy 118Nivolumab 84Gefitinib 73Vinorelbine 64Cetuximab 58atezolizumab 47Afatinib 46durvalumab 44osimertinib 41Radiosurgery 35Ipilimumab 34Drug Therapy 32Taxes 30Albumin-Bound Paclitaxel 29130-nm albumin-bound paclitaxel 29Surgical Procedures, Operative 28Etoposide 25Irinotecan 24Sorafenib 21Cyclophosphamide 20Radiation 19

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Carcinoma, Non-Small-Cell Lung × NVP-BKM120 × Clear all
NCT01570296 2023-03-29

BKM120

National Cancer Centre, Singapore

Phase 1 Completed
38 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01626209 2020-12-09

A Phase I Study of BKM120 in Adult Chinese Patients With Advanced Solid Tumors

Novartis

Phase 1 Completed
32 enrolled
BreastGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms

NCT02128724 2019-08-01

BKM120

University of Oxford

Phase 1 Completed
21 enrolled 23 charts
Thoracic

Hypoxia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01487265 2019-03-06

Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib

SCRI Development Innovations, LLC

Phase 2 Completed
37 enrolled 10 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01723800 2016-09-20

PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung Cancer

City of Hope Medical Center

Phase 1 Completed
9 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01297491 2016-03-11

BASALT-1

Novartis

Phase 2 Completed
63 enrolled 12 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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