Clinical Trials Browser

Phase 2 × Carcinoma, Non-Small-Cell Lung × Radiosurgery × Clear all

NCT03110978 2026-04-16

Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung Cancer

Phase 2 Active not recruiting

EndocrineThoracic

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Carcinoma, Neuroendocrine

NCT06248606 2026-04-08

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung

NCT07517640 2026-04-08

Combining Furmonertinib With Local Therapy for Inoperable Early-stage Lung Cancer: A Phase II Trial

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT03589547 2026-04-02

358

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01803542 2026-03-06

SBRT Lung

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung

NCT04716946 2026-03-04

Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapy

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03965468 2026-02-09

CHESS

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT05830058 2026-01-05

Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

Phase 2 Recruiting

DermatologicGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma

NCT06877299 2026-01-02

Low-Dose Radiation + SBRT + Tislelizumab Plus Platinum-based Chemotherapy in Stage ⅡA-ⅢB Non-small Cell Lung Cancer

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07309952 2025-12-30

SACTION 2501

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT07304739 2025-12-26

Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT02314364 2025-12-16

A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC

Phase 2 Completed

27 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03137771 2025-11-25

Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Phase 2 Active not recruiting

218 enrolled 19 charts

Carcinoma, Non-Small-Cell Lung

NCT06623656 2025-10-23

Preoperative Radioimmunotherapy Versus Chemoimmunotherapy in NSCLC

Phase 2 Recruiting

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT06020066 2025-09-15

SRS for NSCLC With Oligo-residual Intracranial Disease After First-line 3rd Generation EGFR-TKI

Phase 2 Active not recruiting

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05319574 2025-06-12

SACTION01

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT06014827 2025-05-04

Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04767009 2025-04-30

SBRT for Oligo-residual NSCLC After Treatment With PD-1/PD-L1 Immune Checkpoint Inhibitors

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung

NCT04786093 2025-02-13

Durvalumab and Stereotactic Radiotherapy for Advanced NSCLC

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT02839265 2025-01-31

FLT3

Phase 2 Completed

33 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT01753414 2025-01-06

POSTILV

Phase 2 Active not recruiting

44 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04889066 2024-12-20

Durvalumab (MEDI4736) and Radiosurgery (fSRT Vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain Metastases

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT03769103 2024-10-31

Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC

Phase 2 Active not recruiting

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT03217071 2024-10-23

Pembrolizumab With and Without Radiotherapy for Non-Small Cell Lung Cancer

Phase 2 Completed

12 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT04944173 2024-09-03

SCION

Phase 2 Withdrawn

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm, Residual

NCT04908956 2024-06-28

STEREO

Phase 2 Terminated

Carcinoma, Non-Small-Cell Lung

NCT06313541 2024-06-05

Treatment Response Adapted Hybrid Radiotherapy in Metastatic Non-small Cell Lung Cancer Receiving First-line Immunotherapy

Phase 2 Recruiting

Carcinoma, Non-Small-Cell Lung

NCT03497767 2024-05-31

OUTRUN

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung

NCT03511391 2024-01-23

CHEERS

Phase 2 Completed

DermatologicGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Head and Neck Neoplasms, Melanoma

NCT02904954 2023-10-11

Durvalumab (MEDI4736) With or Without SBRT in Clinical Stage I, II and IIIA Non-small Cell Lung Cancer

Phase 2 Completed

60 enrolled 12 charts

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02045446 2023-05-23

Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial

Phase 2 Completed

29 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT03825510 2023-03-06

I-SABR

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung

NCT04650490 2023-03-02

STICk-IM-NSCLC

Phase 2 Withdrawn

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05472467 2022-07-25

IMCORT-2

Phase 2 Unknown

Carcinoma, Non-Small-Cell Lung

NCT00643318 2021-03-05

CyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung Cancer

Phase 2 Unknown

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01573702 2021-01-12

Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR)

Phase 2 Completed

32 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT00547105 2020-08-21

Erlotinib and SBRT in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Phase 2 Completed

24 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02492568 2020-08-17

PEMBRO-RT

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT04255836 2020-02-05

Durvalumab Combined With Chemotherapy and Stereotactic Body Radiotherapy (SBRT) in Patients With Oligometastatic Non-small Cell Lung Cancer (NSCLC)

Phase 2 Unknown

Carcinoma, Non-Small-Cell Lung

NCT01795521 2020-01-31

LungTech

Phase 2 Unknown

Carcinoma, Non-Small-Cell Lung

NCT02285855 2020-01-06

Metformin in Non Small Cell Lung Cancer (NSCLC)

Phase 2 Terminated

27 enrolled 11 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04106180 2019-09-26

SBRT in Combination With Sintilimab and GM-CSF for the Treatment of Advanced NSCLC

Phase 2 Unknown

Carcinoma, Non-Small-Cell Lung

NCT00551369 2019-04-30

Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed By Surgery

Phase 2 Completed

33 enrolled 8 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00087438 2019-01-16

Stereotactic Body Radiation Therapy in Treating Patients With Inoperable Stage I or Stage II Non-Small Cell Lung Cancer

Phase 2 Completed

59 enrolled 10 charts

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02623595 2018-10-15

A Study of SBRT in Combination With rhGM-CSF for Stage IV NSCLC Patients Who Failed in Second-line Chemotherapy

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT03392233 2018-01-05

Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors

Phase 2 Recruiting

BreastGenitourinaryThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Prostatic Neoplasms

NCT01511081 2017-12-07

Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)

Phase 2 Terminated

21 enrolled 5 charts

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Recurrence, Carcinoma, Large Cell

NCT02584699 2015-10-23

Study of Stereotactic Ablative Radiotherapy (SABR) in Elderly Stage I NSCLC

Phase 2 Unknown

Carcinoma, Non-Small-Cell Lung

NCT00385398 2013-09-02

QOL-Stereotactic RadioSurgery, Temozolomide + Erlotinib-Rx of 1-3 Brain Metastases in NSCLC

Phase 2 Withdrawn

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis