Announcements Trials
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Phase

Phase 1 8Phase 1/2 3Phase 2 1

Status

Withdrawn 1Terminated 1Completed 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Thoracic 3

Conditions

Multiple Myeloma 7Hematologic Neoplasms 7Graft vs Host Disease 5Gliosarcoma 5Glioblastoma 5Brain Neoplasms 5Prostatic Neoplasms 4Myelodysplastic Syndromes 4Lymphoma, Non-Hodgkin 4Waldenstrom Macroglobulinemia 3Sarcoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, Follicular 3Lymphoma, B-Cell, Marginal Zone 3Leukemia, Myeloid, Acute 3Leukemia, Lymphocytic, Chronic, B-Cell 3Leukemia 3Hodgkin Disease 3Carcinoma, Non-Small-Cell Lung 3Tuberous Sclerosis 2Oligodendroglioma 2Neurofibrosarcoma 2Myeloproliferative Disorders 2Lymphoma, Mantle-Cell 2Lymphoma 2Lung Neoplasms 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Glioma 2Burkitt Lymphoma 2Bronchiolitis Obliterans Syndrome 2

Interventions

pembrolizumab 91Carboplatin 73Pemetrexed 58Nivolumab 50Docetaxel 47Cisplatin 47Paclitaxel 46Erlotinib Hydrochloride 37Radiotherapy 30Gemcitabine 27osimertinib 23Cetuximab 23Bevacizumab 21Ipilimumab 18Radiosurgery 14130-nm albumin-bound paclitaxel 14Taxes 13Gefitinib 13Cyclophosphamide 13avelumab 12atezolizumab 12durvalumab 11Albumin-Bound Paclitaxel 11cemiplimab 9Radiation 8Drug Therapy 8alectinib 7Injections 7Etoposide 7trametinib 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1/2 × Carcinoma, Non-Small-Cell Lung × Sirolimus × Clear all
NCT01737502 2025-09-05

Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer

Mayo Clinic

Phase 1/2 Completed
29 enrolled 16 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT00923273 2019-11-26

Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
42 enrolled 16 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00098462 2012-10-04

Gefitinib and Sirolimus in Treating Patients With Recurrent or Refractory Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Jonsson Comprehensive Cancer Center

Phase 1/2 Withdrawn
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

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