Clinical Trials

535 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03589547 2026-04-02

358

11 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04245514 2026-04-02

Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC)

90 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04351256 2026-03-27

TRADE-hypo

51 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05696782 2026-03-23

Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer

28 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04499053 2026-03-16

Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer

18 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06083454 2026-03-13

Ascorbate With Durvalumab in Non-Small Cell Lung Cancer (NSCLC)

1 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04716946 2026-03-04

Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapy

13 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04585477 2026-02-10

Adjuvant ctDNA-Adapted Personalized Treatment in Early Stage NSCLC (ADAPT-E)

80 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05443971 2026-02-06

Durvalumab and Grid Therapy for Non-small Cell Lung Cancer in Progression During or After Treatment With PACIFIC Regimen

4 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03141359 2026-02-05

Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC

61 enrolled 25 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06333678 2026-01-29

A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)

10 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06634199 2026-01-28

SIENNA

Recruiting

50 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05206812 2026-01-27

Window of Opportunity Trial of Durvalumab (MEDI4736) to Identify Immune Dynamics in Operable Non-small Cell Lung Cancer (NSCLC) (MIRACLE)

25 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04748419 2026-01-22

Safety & Efficacy of Consolidative Hypofractionated Radiation Therapy for Boosting Residual Lung Cancer With Durvalumab

6 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06124118 2026-01-08

NOVOCURE

Phase 1 Recruiting

30 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04224337 2025-12-31

Phase II Study of Durvalumab ,Doxorubicin, and Ifosfamide in Pulmonary Sarcomatoid Carcinoma

16 enrolled

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT07247786 2025-12-30

MIGRANT

68 enrolled

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Respiratory Tract Neoplasms

NCT07146230 2025-12-24

SPRINT 2

52 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04550104 2025-12-19

CONCORDE

Phase 1 Recruiting

200 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04765709 2025-12-16

BRIDGE

10 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03999710 2025-11-28

Determining Whether Durvalumab in Combination With Radiation Therapy Can Prevent the Progression of Non-Small Cell Lung Cancer

61 enrolled

BreastDermatologicGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Recurrence

NCT02639026 2025-11-25

Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers

Phase 1 Completed

53 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT04895579 2025-11-18

LCD

Phase 1 Completed

11 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03916419 2025-11-12

Magnetic Resonance-Guided Hypofractionated Adaptive Radiation Therapy With Concurrent Chemotherapy and Consolidation Durvalumab for Inoperable Stage IIB, IIIA, and Select IIIB and IIIC Non-small Cell Lung Cancer

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03581487 2025-11-05

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Phase 1/2 Completed

40 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02572843 2025-10-28

Anti-PD-L1 in Stage IIIA(N2) Non-small Cell Lung Cancer (NSCLC)

68 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03237377 2025-10-14

Neoadjuvant Immunoradiation for Resectable Non-Small Cell Lung Cancer

9 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung

NCT04108026 2025-10-03

SAVIMMUNE

50 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03620669 2025-08-15

1st Line Durvalumab in PS 2 NSCLC Patients

48 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03148327 2025-07-15

Astra Zeneca (Immuno Stereotactic Ablative Body Radiotherapy) ISABR Study: Randomized Phase I/II Study of Stereotactic Body Radiotherapy

18 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04062708 2025-07-08

CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancer

38 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04905316 2025-06-17

CHORUS

41 enrolled

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT06998719 2025-05-31

ACCESS

80 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04441138 2025-05-28

ESR1814205

10 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung

NCT02664935 2025-05-21

National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer

423 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms

NCT02983578 2025-05-06

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

39 enrolled

GastrointestinalThoracic

Turcot syndrome, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04585490 2025-05-06

Personalized Escalation of Consolidation Treatment Following Chemoradiotherapy and Immunotherapy in Stage III NSCLC in Stage III NSCLC

Phase 3 Recruiting

48 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04003246 2025-03-21

Phase II Concurrent Durvalumab and Radiotherapy for for Stage III Non-Small Cell Lung Cancer

10 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05911308 2025-03-21

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

1 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04786093 2025-02-13

Durvalumab and Stereotactic Radiotherapy for Advanced NSCLC

52 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04230408 2025-02-11

PACIFIC BRAZIL

48 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06191250 2025-02-03

--SuPERIOR Trial--

10 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04597671 2025-01-29

NVALT28

170 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04889066 2024-12-20

Durvalumab (MEDI4736) and Radiosurgery (fSRT Vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain Metastases

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT04287894 2024-11-06

Induction

18 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05757843 2024-09-19

Using Circulating Tumor DNA to Personalize Duration of Consolidation Durvalumab

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT02492867 2024-09-03

A Pilot Study of Response-Driven Adaptive Radiation Therapy for Patients With Locally Advanced Non-Small Cell Lung Cancer

Phase NA Completed

49 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT04944173 2024-09-03

SCION

Phase 2 Withdrawn

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm, Residual

NCT04348292 2024-08-22

Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer

3 enrolled 7 charts