Announcements Trials
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Phase

Phase 1 2Phase 1/2 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 2Gastrointestinal 2Gynecologic 1

Conditions

Carcinoma, Non-Small-Cell Lung 85Neoplasm Metastasis 74Colorectal Neoplasms 74Neoplasms 72Leukemia, Myeloid, Acute 62Breast Neoplasms 54Prostatic Neoplasms 47Multiple Myeloma 47Ovarian Neoplasms 42Pancreatic Neoplasms 41Squamous Cell Carcinoma of Head and Neck 38Melanoma 36Recurrence 33Glioblastoma 33Lung Neoplasms 31Myelodysplastic Syndromes 30Triple Negative Breast Neoplasms 29Lymphoma, Non-Hodgkin 29Advanced Solid Tumors 27Endometrial Neoplasms 26Stomach Neoplasms 24Small Cell Lung Carcinoma 24Carcinoma, Renal Cell 24Precursor Cell Lymphoblastic Leukemia-Lymphoma 23Brain Neoplasms 22Carcinoma, Hepatocellular 21Sarcoma 19Lymphoma, B-Cell 19Lymphoma, Large B-Cell, Diffuse 18Esophageal Neoplasms 18

Interventions

pembrolizumab 1Pemetrexed 1Paclitaxel 1Oxaliplatin 1Leucovorin 1Gemcitabine 1Fluorouracil 1Cisplatin 1Cetuximab 1Carboplatin 1Bevacizumab 1Albumin-Bound Paclitaxel 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Carcinoma, Pancreatic Ductal × 30 days × Clear all
NCT06704724 2026-05-22

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

Pfizer

Phase 1 Terminated
30 enrolled
GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT05462717 2026-05-15

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Revolution Medicines, Inc.

Phase 1 Active not recruiting
222 enrolled
GastrointestinalGynecologicThoracic

Appendiceal Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Carcinoma, Pancreatic Ductal

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