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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Multiple Myeloma 237Precursor Cell Lymphoblastic Leukemia-Lymphoma 69Recurrence 36Burkitt Lymphoma 34Leukemia 32Lymphoma 30Neoplasms, Plasma Cell 22Lymphoma, Non-Hodgkin 19Immunoglobulin Light-chain Amyloidosis 18Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 17Lymphoma, Mantle-Cell 16Neoplasms 15Nausea 15Lymphoma, Large B-Cell, Diffuse 15Vomiting 14Hodgkin Disease 13Breast Neoplasms 12Waldenstrom Macroglobulinemia 11Leukemia, Biphenotypic, Acute 11Lymphoma, Follicular 10Lymphoma, B-Cell, Marginal Zone 10Amyloidosis 10Lung Neoplasms 9Smoldering Multiple Myeloma 8Prostatic Neoplasms 8Neoplasm Metastasis 8Leukemia, Myeloid, Acute 8Hematologic Neoplasms 7Blast Crisis 7Lymphoma, T-Cell, Cutaneous 6

Interventions

Cisplatin 7Etoposide 6pembrolizumab 4Topotecan 4Pemetrexed 4Carboplatin 4Gemcitabine 3belinostat 2Temozolomide 2RRx-001 2Paclitaxel 2vosaroxin 1vinflunine 1veliparib 1taxane 1sagopilone 1sacituzumab govitecan 1pomalidomide 1lurtotecan 1liposomal doxorubicin 1etoposide phosphate 1enzalutamide 1bemiparin 1belotecan 1atezolizumab 1apalutamide 1alvocidib 1abiraterone 1Vinorelbine 1Tomography, X-Ray Computed 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Carcinoma, Small Cell × Calcium Dobesilate × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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