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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Multiple Myeloma 17Burkitt Lymphoma 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Rectal Neoplasms 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Anaplastic 2Lung Neoplasms 2Leukemia, Biphenotypic, Acute 2Immunoglobulin Light-chain Amyloidosis 2Down Syndrome 2Waldenstrom Macroglobulinemia 1Uterine Cervical Neoplasms 1Spinal Cord Neoplasms 1Small Cell Lung Carcinoma 1Rhabdoid Tumor 1Recurrence 1Prolactinoma 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Plasmacytoma 1Pituitary Neoplasms 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1Oligodendroglioma 1Neoplasms, Plasma Cell 1Mesothelioma 1Medulloblastoma 1Lymphoma, T-Cell 1Lymphoma, Non-Hodgkin 1Lymphoma, Follicular 1

Interventions

veliparib 1sacituzumab govitecan 1alvocidib 1Topotecan 1Tomography, X-Ray Computed 1Temozolomide 1Positron-Emission Tomography 1Podophyllotoxin 1Platinum 1Histamine Antagonists 1Etoposide 1Epinephrine 1Electrocardiography 1Diphenhydramine 1Dexamethasone 1Depsipeptides 1Cisplatin 1Calcium Dobesilate 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Carcinoma, Small Cell × Calcium Dobesilate × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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