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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Multiple Myeloma 107Precursor Cell Lymphoblastic Leukemia-Lymphoma 38Leukemia 23Lymphoma 20Recurrence 16Burkitt Lymphoma 16Lymphoma, Mantle-Cell 13Neoplasms, Plasma Cell 11Lymphoma, Non-Hodgkin 11Waldenstrom Macroglobulinemia 9Lymphoma, Follicular 9Immunoglobulin Light-chain Amyloidosis 9Hodgkin Disease 9Breast Neoplasms 9Vomiting 8Neoplasms 8Nausea 8Lymphoma, B-Cell, Marginal Zone 8Lymphoma, Large B-Cell, Diffuse 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, T-Cell, Cutaneous 6Leukemia, Lymphocytic, Chronic, B-Cell 6Amyloidosis 6Leukemia, Myeloid, Acute 5Smoldering Multiple Myeloma 4Sezary Syndrome 4Mycosis Fungoides 4Lymphoma, Large-Cell, Immunoblastic 4Lung Neoplasms 4Blast Crisis 4

Interventions

Topotecan 4Cisplatin 4Etoposide 3belinostat 2Pemetrexed 2Paclitaxel 2Carboplatin 2vosaroxin 1vinflunine 1veliparib 1taxane 1sagopilone 1pembrolizumab 1lurtotecan 1liposomal doxorubicin 1belotecan 1Vinorelbine 1Tomography, X-Ray Computed 1Temozolomide 1Taxes 1Sorafenib 1RRx-001 1Quality of Life 1Positron-Emission Tomography 1Podophyllotoxin 1Platinum 1Patient Reported Outcome Measures 1PT-100 dipeptide 1Nortriptyline 1Molecular Diagnostic Techniques 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Carcinoma, Small Cell × Calcium Dobesilate × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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