Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Multiple Myeloma 33Precursor Cell Lymphoblastic Leukemia-Lymphoma 18Neoplasms, Plasma Cell 14Lymphoma 14Leukemia 13Burkitt Lymphoma 10Lymphoma, Non-Hodgkin 7Lymphoma, Follicular 5HIV Infections 5Brain Neoplasms 5Acquired Immunodeficiency Syndrome 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Lymphoma, Mantle-Cell 4Leukemia, Biphenotypic, Acute 4Lymphoma, Large-Cell, Anaplastic 3Lymphoma, B-Cell, Marginal Zone 3Lung Neoplasms 3Leukemia, Lymphocytic, Chronic, B-Cell 3Rectal Neoplasms 2Myelodysplastic Syndromes 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myelomonocytic, Chronic 2Immunoglobulin Light-chain Amyloidosis 2Hematologic Diseases 2Down Syndrome 2Dendritic Cell Sarcoma, Interdigitating 2Central Nervous System Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Anemia, Refractory, with Excess of Blasts 2

Interventions

veliparib 1sacituzumab govitecan 1alvocidib 1Topotecan 1Tomography, X-Ray Computed 1Temozolomide 1Positron-Emission Tomography 1Podophyllotoxin 1Platinum 1Histamine Antagonists 1Etoposide 1Epinephrine 1Electrocardiography 1Diphenhydramine 1Dexamethasone 1Depsipeptides 1Cisplatin 1Calcium Dobesilate 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Carcinoma, Small Cell × Dexamethasone × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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