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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Prostatic Neoplasms 8Neuroendocrine Tumors 3Esophageal Neoplasms 3Carcinoma, Hepatocellular 3Lymphoma, Non-Hodgkin 2Lymphoma 2Disease 2Brain Neoplasms 2Vulvar Neoplasms 1Vulvar Diseases 1Vasculitis 1Uterine Cervical Neoplasms 1Uterine Cervical Dysplasia 1Urinary Bladder Neoplasms 1Unspecified Adult Solid Tumor, Protocol Specific 1Stomach Neoplasms 1Solid Tumor, Adult 1Smoking Cessation 1Small Cell Lung Carcinoma 1Rectal Neoplasms 1Papillomavirus Infections 1Pancreatic Neoplasms 1Pancreatic Cystic Neoplasms 1Osteomyelitis 1Nose Neoplasms 1Neurodegenerative Diseases 1Neoplasms 1Neoplasm Metastasis 1Myelodysplastic Syndromes 1Multiple Pulmonary Nodules 1

Interventions

Topotecan 4Cisplatin 4Etoposide 3belinostat 2Pemetrexed 2Paclitaxel 2Carboplatin 2vosaroxin 1vinflunine 1veliparib 1taxane 1sagopilone 1pembrolizumab 1lurtotecan 1liposomal doxorubicin 1belotecan 1Vinorelbine 1Tomography, X-Ray Computed 1Temozolomide 1Taxes 1Sorafenib 1RRx-001 1Quality of Life 1Positron-Emission Tomography 1Podophyllotoxin 1Platinum 1Patient Reported Outcome Measures 1PT-100 dipeptide 1Nortriptyline 1Molecular Diagnostic Techniques 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Carcinoma, Small Cell × Positron-Emission Tomography × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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