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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Glioblastoma 31Gliosarcoma 27Astrocytoma 22Brain Neoplasms 17Central Nervous System Neoplasms 16Oligodendroglioma 12Medulloblastoma 9Neuroblastoma 7Glioma 7Choroid Plexus Neoplasms 7Sarcoma 6Melanoma 6Familial ependymoma 6Optic Nerve Glioma 5Spinal Cord Neoplasms 4Rhabdoid Tumor 4Neuroectodermal Tumors, Primitive, Peripheral 4Ependymoma 4Uveal Melanoma 3Rhabdomyosarcoma 3Ovarian Neoplasms 3Osteosarcoma 3Neuroectodermal Tumors, Primitive 3Breast Neoplasms 3Wilms Tumor 2Testicular Neoplasms 2Teratoma 2Small Cell Lung Carcinoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pinealoma 2

Interventions

veliparib 1sacituzumab govitecan 1alvocidib 1Topotecan 1Tomography, X-Ray Computed 1Temozolomide 1Positron-Emission Tomography 1Podophyllotoxin 1Platinum 1Histamine Antagonists 1Etoposide 1Epinephrine 1Electrocardiography 1Diphenhydramine 1Dexamethasone 1Depsipeptides 1Cisplatin 1Calcium Dobesilate 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Carcinoma, Small Cell × Temozolomide × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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