Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Small Cell Lung Carcinoma 10Ovarian Neoplasms 9Carcinoma, Ovarian Epithelial 8Neuroblastoma 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Leukemia 5Fallopian Tube Neoplasms 5Uterine Cervical Neoplasms 4Myelodysplastic Syndromes 4Lung Neoplasms 4Leukemia, Myelomonocytic, Chronic 4Leukemia, Myeloid, Acute 4Unspecified Adult Solid Tumor, Protocol Specific 3Sarcoma 3Polycythemia Vera 3Neuroectodermal Tumors, Primitive, Peripheral 3Neoplasms 3Neoplasm Metastasis 3Lymphoma 3Ganglioneuroblastoma 3Carcinoma, Non-Small-Cell Lung 3Anemia, Refractory, with Excess of Blasts 3Thrombocythemia, Essential 2Primary Myelofibrosis 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myelomonocytic, Acute 2Leukemia, Monocytic, Acute 2Leukemia, Megakaryoblastic, Acute 2Leukemia, Erythroblastic, Acute 2Carcinoma, Neuroendocrine 2

Interventions

veliparib 1sacituzumab govitecan 1alvocidib 1Topotecan 1Tomography, X-Ray Computed 1Temozolomide 1Positron-Emission Tomography 1Podophyllotoxin 1Platinum 1Histamine Antagonists 1Etoposide 1Epinephrine 1Electrocardiography 1Diphenhydramine 1Dexamethasone 1Depsipeptides 1Cisplatin 1Calcium Dobesilate 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Carcinoma, Small Cell × Topotecan × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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