Announcements Trials
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Phase

Phase 2 3Phase 1 1

Status

Withdrawn 1Unknown 1Terminated 1Recruiting 1

Sponsor Class

OTHER 4INDUSTRY 2OTHER_GOV 1

Study Type

Interventional 4

Sponsor

Cancer Type

Tumor-Agnostic 2Thoracic 1Dermatologic 1

Conditions

Carcinoma, Non-Small-Cell Lung 25Squamous Cell Carcinoma of Head and Neck 10Lung Neoplasms 10Neoplasms 6Neoplasm Metastasis 6Head and Neck Neoplasms 6Esophageal Squamous Cell Carcinoma 5Breast Neoplasms 5Pancreatic Neoplasms 4Carcinoma, Squamous Cell 4Stomach Neoplasms 3Esophageal Neoplasms 3Brain Neoplasms 3Prostatic Neoplasms 2Non-small-cell Lung Cancer With Somatic EGFR Mutations 2NSCLC 2Glioblastoma 2Colorectal Neoplasms 2Adenocarcinoma of Lung 2Urinary Bladder Neoplasms 1Urethral Neoplasms 1Ureteral Neoplasms 1Unilateral HER2 Positive Breast Cancer 1Triple Negative Breast Neoplasms 1Thrombocytosis 1Thoracic Neoplasms 1Squamous Cell Cancers of the Head and Neck 1Solid Tumors 1Small Cell Lung Carcinoma 1Skin Neoplasms 1

Interventions

Cisplatin 55Radiotherapy 33Cetuximab 25Paclitaxel 23Carboplatin 23Radiotherapy, Intensity-Modulated 21pembrolizumab 19Docetaxel 17Fluorouracil 16Nivolumab 14Drug Therapy 11Radiation 9Erlotinib Hydrochloride 8Blood Specimen Collection 8durvalumab 7Magnetic Resonance Spectroscopy 7Surveys and Questionnaires 6atezolizumab 5Surgical Procedures, Operative 5Radiosurgery 5Esophagectomy 5Chemoradiotherapy 5olaparib 4dacomitinib 4Leucovorin 4Cyclophosphamide 4Capecitabine 4Biopsy 4Afatinib 4fludarabine phosphate 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × Carcinoma, Squamous Cell × Afatinib × Clear all
NCT05070403 2026-04-01

Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma

H. Lee Moffitt Cancer Center and Research Institute

Phase 2 Recruiting
25 enrolled
Dermatologic

Carcinoma, Squamous Cell, Skin Neoplasms

NCT04533321 2020-08-31

A Biomarker-implemented Clinical Study Evaluating Mutations in MET and TP53 in a Population of Treatment-refractory Squamous Cell Carcinoma

National University Hospital, Singapore

Phase 2 Unknown
20 enrolled
Tumor-Agnostic

Carcinoma, Squamous Cell

NCT03652233 2019-06-20

Afatinib and Nivolumab as Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Vanderbilt-Ingram Cancer Center

Phase 1 Withdrawn
Tumor-Agnostic

Carcinoma, Squamous Cell

NCT02271906 2019-04-30

The ATTAIN Study: A Therapeutic Trial of Afatinib In the Neoadjuvant Setting

M.D. Anderson Cancer Center

Phase 2 Terminated
2 enrolled 8 charts
Thoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms

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