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Phase

Phase 2 3Phase 3 2

Status

Completed 4Not yet recruiting 1

Sponsor Class

OTHER 2INDUSTRY 2OTHER_GOV 1

Study Type

Interventional 5

Sponsor

Cancer Type

Head & Neck 3Dermatologic 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 250Leukemia 186Lymphoma 137Leukemia, Myeloid, Acute 103Burkitt Lymphoma 90Myelodysplastic Syndromes 79Lymphoma, Non-Hodgkin 65Breast Neoplasms 60Lymphoma, Large B-Cell, Diffuse 59Leukemia, Lymphocytic, Chronic, B-Cell 49Lymphoma, Mantle-Cell 47Hodgkin Disease 47Graft vs Host Disease 46Lymphoma, Follicular 45Leukemia, Myeloid, Accelerated Phase 45Multiple Myeloma 39Leukemia, Myeloid, Chronic-Phase 39Congenital Abnormalities 39Myeloproliferative Disorders 38Blast Crisis 38Leukemia, Myelomonocytic, Chronic 37Leukemia, Biphenotypic, Acute 35Recurrence 34Lymphoma, Large-Cell, Immunoblastic 33Lymphoma, B-Cell, Marginal Zone 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Osteosarcoma 29Primary Myelofibrosis 27Neoplasms, Plasma Cell 25Leukemia, Myelogenous, Chronic, BCR-ABL Positive 25

Interventions

Cisplatin 76Radiotherapy 44Cetuximab 40pembrolizumab 39Paclitaxel 34Carboplatin 33Docetaxel 30Fluorouracil 25Radiotherapy, Intensity-Modulated 23Nivolumab 18Drug Therapy 14Radiation 12Erlotinib Hydrochloride 9cemiplimab 8Magnetic Resonance Spectroscopy 8Blood Specimen Collection 8130-nm albumin-bound paclitaxel 8durvalumab 7atezolizumab 7Cyclophosphamide 7Afatinib 7Surveys and Questionnaires 6Surgical Procedures, Operative 6Panitumumab 6Leucovorin 6Esophagectomy 6Chemoradiotherapy 6fludarabine 5aldesleukin 5Radiosurgery 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Carcinoma, Squamous Cell × Methotrexate × Clear all
NCT07361133 2026-04-16

Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer

National Cancer Institute, Egypt

Phase 2 Not yet recruiting
120 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT02252042 2023-07-17

MK-3475-040

Merck Sharp & Dohme LLC

Phase 3 Completed
495 enrolled 32 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Squamous Cell

NCT05315128 2022-04-07

Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin Cancers

Zagazig University

Phase 2 Completed
60 enrolled
Dermatologic

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Keratoacanthoma

NCT01345682 2018-02-15

LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

Boehringer Ingelheim

Phase 3 Completed
483 enrolled 21 charts
Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT01528163 2017-06-14

RACATREX

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Phase 2 Completed
101 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

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