Clinical Trials

308 enrolled 17 charts 3 FDA

Anus Neoplasms, Carcinoma, Squamous Cell

NCT04180215 2025-09-15

A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers

198 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms, Neoplasms, Squamous Cell

NCT02013154 2025-08-03

P102

151 enrolled

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT06112535 2025-06-25

Prospective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic Surgery

Phase NA Completed

60 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT00472459 2025-04-18

Photodynamic Therapy (PDT) With Metvix® 160 Milligrams/Gram Cream in Organ Transplant Participants With Non-melanoma Skin Cancer

82 enrolled 20 charts

Bowen's Disease, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Warts, Keratosis, Actinic

NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

58 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT03257267 2025-04-08

Study of Cemiplimab in Adults With Cervical Cancer

608 enrolled 18 charts

Carcinoma, Squamous Cell, Neoplasm Metastasis, Recurrence

NCT05337163 2025-03-21

A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China

1,564 enrolled

Adenocarcinoma, Bronchitis, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Pneumonia, Pulmonary Fibrosis, Respiratory Tract Infections, Tuberculosis, Carcinoma, Adenosquamous, Carcinoma, Large Cell, Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic, Small Cell Lung Carcinoma

NCT03058289 2025-02-27

IT-01

BreastGastrointestinalHead & NeckLymphoidSarcomaThoracic

111 enrolled 21 charts

Diabetes Mellitus, Insulin-Dependent, 12, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT04969419 2025-01-14

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

75,771 enrolled 19 charts

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Vitiligo, Keratosis, Actinic

NCT06690086 2024-12-09

DERM-SUCCESS

1,028 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms

NCT03284424 2024-08-23

MK-3475-629

159 enrolled 16 charts 3 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Squamous Cell

NCT03847519 2024-06-04

Study of ADXS-503 With or Without Pembro in Subjects With Metastatic Non-Small Cell Lung Cancer

24 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell

NCT02164461 2024-05-20

Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer

12 enrolled 18 charts

GynecologicThoracic

Adenocarcinoma, Carcinoma, Carcinoma, Squamous Cell, Uterine Cervical Diseases, Uterine Cervical Neoplasms, Genital Diseases, Female, Genital Neoplasms, Female, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Urogenital Neoplasms, Uterine Diseases, Uterine Neoplasms, Carcinoma, Adenosquamous, Carcinoma, Small Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma

NCT03689712 2023-10-24

ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients

455 enrolled 11 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis, Oral Ulcer

NCT03748134 2023-10-24

Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )

746 enrolled

Esophageal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Neoplasms, Squamous Cell

NCT02499120 2023-09-08

Safety And Efficacy Study Of Palbociclib Plus Cetuximab Versus Cetuximab To Treat Head And Neck Cancer

125 enrolled 21 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02252042 2023-07-17

MK-3475-040

495 enrolled 32 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Squamous Cell

NCT05126173 2023-06-28

DERM US and EU Validation Study

1,111 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT03989115 2023-06-26

Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

113 enrolled 22 charts

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Gastrointestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Noonan Syndrome, Ovarian Neoplasms, Pancreatic Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Neoplasms, Squamous Cell

NCT03841110 2023-05-01

FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

37 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Microsatellite Instability, Small Cell Lung Carcinoma

NCT04196283 2023-02-27

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Neoplasms

NCT01607905 2023-01-26

Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer

CNSDermatologicGastrointestinal

192 enrolled 29 charts

Adenocarcinoma, Carcinoma, Squamous Cell, Glioblastoma, Melanoma, Colorectal Neoplasms

NCT02844777 2023-01-12

Efficacy and Safety of VDA-1102 Ointment in the Treatment of Actinic Keratosis

DermatologicOther neoplasm

93 enrolled 13 charts

Carcinoma, Squamous Cell, Precancerous Conditions, Keratosis, Actinic

NCT01016899 2022-12-13

Electronic Brachytherapy for the Treatment of NMSC

187 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Neoplasms

NCT03237325 2022-11-08

DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer

266 enrolled 11 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis

NCT00446446 2022-10-05

PRISM (Panitumumab Regimen In Second-line Monotherapy of Head and Neck Cancer)

52 enrolled 17 charts

Carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasms

NCT05125354 2022-06-01

A Retrospective Analysis to Evaluate Long Term Outcomes of SCC Patients Previously Treated With Alpha DaRT

33 enrolled

Tumor-Agnostic

Carcinoma, Squamous Cell

NCT01391143 2022-02-08

Safety Study of MGA271 in Refractory Cancer

BreastDermatologicGenitourinaryHead & NeckThoracic

179 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Prostatic Neoplasms, Triple Negative Breast Neoplasms

NCT01077817 2022-02-03

Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of Osteoporosis (MK-0217A-352)

684,815 enrolled 6 charts

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02737501 2021-08-20

ALTA-1L

275 enrolled 23 charts 3 FDA

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT03015883 2021-01-13

DaRT

Phase NA Completed

28 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Skin Neoplasms

NCT02027428 2020-08-17

Safety and Efficacy Study of Abraxane as Maintenance Treatment After Abraxane Plus Carboplatin in 1st Line Stage IIIB / IV Squamous Cell Non-small Cell Lung Cancer

427 enrolled 29 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms

NCT00073398 2020-05-28

Vaccine Treatment for Advanced Non-Small Cell Lung Cancer

54 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT01017185 2019-05-23

Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions

BreastDermatologicHead & Neck

28 enrolled

Breast Neoplasms, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma

NCT03109158 2019-04-29

NC-6004 With 5-FU and Cetuximab for Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

1 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT00652080 2019-03-05

An Open-Label Safety Study of API 31510 in a Topical Cream for in Situ Cutaneous Squamous Cell Carcinoma (SCCIS)

35 enrolled 9 charts

Tumor-Agnostic

Carcinoma, Squamous Cell

NCT02241369 2018-11-16

Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies

3 enrolled

Tumor-Agnostic

Carcinoma, Squamous Cell, Neoplasms

NCT00500760 2018-10-17

Study of Addition of Panitumumab to Chemoradiation Therapy in Patients With Locally Advanced Head and Neck Cancer

153 enrolled 18 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02151149 2018-09-24

ABOUND 70+

Phase 4 Completed

143 enrolled 25 charts

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT01252628 2018-05-16

Phase 1 and 2 Study of PX-866 and Cetuximab

178 enrolled

Carcinoma, Squamous Cell, Hereditary Sensory and Autonomic Neuropathies, Recurrence, Colorectal Neoplasms

NCT01345682 2018-02-15

LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

483 enrolled 21 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02409628 2017-09-15

EktoTherix™ Regenerative Tissue Scaffold for Repair of Surgical Excision Wounds

Phase NA Completed

12 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT01807546 2017-06-26

Oral Rigosertib for Squamous Cell Carcinoma

GastrointestinalHead & Neck

64 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02107235 2017-06-23

Platinum-based Chemoradiotherapy and Rigosertib in Head and Neck Cancer

2 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00547157 2017-03-15

Radiotherapy Plus Panitumumab Compared to Chemoradiotherapy With Unresected, Locally Advanced Squamous Cell Carcinoma of the Head and Neck

152 enrolled 18 charts