Announcements Trials
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Phase

Phase 2 2Phase 1/2 1

Status

Completed 4Active not recruiting 3Terminated 2Unknown 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Genitourinary 3Thoracic 1Head & Neck 1Gastrointestinal 1Dermatologic 1

Conditions

Carcinoma, Non-Small-Cell Lung 68Lung Neoplasms 18Neoplasms 7Neoplasm Metastasis 7Melanoma 5Carcinoma 5Mesothelioma, Malignant 4Colorectal Neoplasms 4Parkinson Disease 4, Autosomal Dominant Lewy Body 3Ovarian Neoplasms 3Carcinoma, Transitional Cell 3Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Non-Squamous Non-small Cell Lung Cancer 2Non-Small Cell Lung Cancer Metastatic 2Non Small Cell Lung Carcinoma NSCLC 2Mesothelioma 2Endometrial Neoplasms 2Brain Neoplasms 2Advanced Solid Tumors 2Uveal Melanoma 1Uterine Cervical Neoplasms 1Stomach Neoplasms 1Solitary Fibrous Tumor, Pleural 1Salivary Gland Neoplasms 1Resectable Stage IIA to IIIB Non-small Cell Lung Cancer 1Resectable Non-small Cell Lung Cancer 1Recurrent Metastatic Non-Squamous Non Small Cell Lung Cancer 1Rectal Neoplasms 1Primary Myelofibrosis 1

Interventions

pembrolizumab 15Nivolumab 10avelumab 9atezolizumab 8Gemcitabine 8Cisplatin 8Magnetic Resonance Spectroscopy 6durvalumab 5Specimen Handling 5Docetaxel 5Carboplatin 5Paclitaxel 4Ipilimumab 4tislelizumab 3sacituzumab govitecan 3enfortumab vedotin 3Taxes 3Pemetrexed 3Mitomycin 3eribulin 2erdafitinib 2cabozantinib 2Doxorubicin 2CTLA-4 Antigen 2ALT-803 2zimberelimab 1veliparib 1urelumab 1tazemetostat 1spartalizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Active not recruiting × Carcinoma, Transitional Cell × Pemetrexed × Clear all
NCT05335941 2026-03-04

A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
10 enrolled
Genitourinary

Carcinoma, Transitional Cell, Neoplasm Metastasis

NCT03744793 2026-01-09

Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
18 enrolled
Genitourinary

Carcinoma, Transitional Cell

NCT04198766 2025-12-18

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Inhibrx Biosciences, Inc

Phase 1/2 Active not recruiting
296 enrolled
DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Lung Neoplasms, Melanoma, Mouth Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Oropharyngeal Neoplasms, Stomach Neoplasms, Neoplasms, Squamous Cell

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