Clinical Trials

50 enrolled

Carcinoma, Neoplasms

NCT06835569 2026-04-03

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

188 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05768932 2026-03-27

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

BreastGastrointestinalOther hematologic neoplasm

260 enrolled

Carcinoma, Stomach Neoplasms, Leukemia, Myeloid, Acute, Triple Negative Breast Neoplasms

NCT05873686 2026-03-03

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

GenitourinaryOther solid neoplasmThoracic

140 enrolled

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Kidney Neoplasms, Mesothelioma, Neoplasms

NCT05068102 2026-02-18

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

Phase 1 Active not recruiting

DermatologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT04752215 2026-02-02

A Study Evaluating Different Doses of BI 765049 When Given Alone and When Given With Ezabenlimab to Patients With Advanced Solid Tumors Expressing the Protein B7-H6 on the Cell Surface

GastrointestinalHead & Neck

67 enrolled

Carcinoma, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06457997 2026-01-29

A Study of PHN-010 in Patients With Advanced Solid Tumors

GastrointestinalGynecologicThoracic

26 enrolled

Carcinoma, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT05165433 2025-12-16

FORTIFY

Carcinoma, Neoplasm Metastasis

NCT02592577 2025-12-09

MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC

28 enrolled

Phase 1 Active not recruiting

Carcinoma, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04603287 2025-09-26

A Study of SI-B001, an EGFR/HER3 Bispecific Antibody, in Locally Advanced or Metastatic Epithelial Tumors

60 enrolled

GastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Colorectal Neoplasms

NCT05226507 2025-08-08

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Phase 1 Active not recruiting

45 enrolled

Gynecologic

Adenocarcinoma, Carcinoma, Neoplasms, Ovarian Neoplasms

NCT04053283 2025-03-24

STAR

186 enrolled

Carcinoma, Neoplasm Metastasis, Virus Diseases

NCT05043714 2025-03-24

NEBULA

30 enrolled

Carcinoma, Neoplasm Metastasis

NCT06069570 2025-03-05

Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

48 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT04862780 2025-02-10

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

177 enrolled

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT05241873 2025-02-10

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

103 enrolled

CNSThoracic

Adenocarcinoma, Brain Neoplasms, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02834611 2024-05-29

Ceramide NanoLiposome in Patients With Advanced Solid Tumors

Carcinoma, Neoplasms

NCT02164461 2024-05-20

Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer

12 enrolled 18 charts

GynecologicThoracic

Adenocarcinoma, Carcinoma, Carcinoma, Squamous Cell, Uterine Cervical Diseases, Uterine Cervical Neoplasms, Genital Diseases, Female, Genital Neoplasms, Female, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Urogenital Neoplasms, Uterine Diseases, Uterine Neoplasms, Carcinoma, Adenosquamous, Carcinoma, Small Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma

NCT02867007 2024-04-25

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

36 enrolled

Carcinoma, Neoplasms

NCT00728390 2024-04-22

A Safety And Efficacy Study Of The Combination Of Oral PF-00299804 And Intravenous CP-751,871 Given Every 3 Weeks

74 enrolled

Carcinoma, Neoplasm Metastasis

NCT06307093 2024-03-12

Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms

DermatologicHead & NeckThoracic

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Lung Neoplasms, Melanoma, Neoplasms

NCT04149691 2024-02-07

Safety, Tolerability and Pharmacokinetics of Oral CPL304110, in Adult Subjects With Advanced Solid Malignancies

GastrointestinalGenitourinaryGynecologicSarcoma

42 enrolled

Urinary Bladder Neoplasms, Carcinoma, Neoplasms, Sarcoma, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT05969041 2024-01-18

MYE Symphony

BreastGastrointestinalGynecologicThoracic

48 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01421524 2023-12-12

Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma

CNSGastrointestinalLymphoidPlasma cell

271 enrolled

Carcinoma, Glioblastoma, Carcinoma, Hepatocellular, Lymphoma, Multiple Myeloma, Neoplasms, Lymphoma, Large B-Cell, Diffuse

NCT05498597 2023-10-19

AMT-151 in Patients With Selected Advanced Solid Tumours

BreastGynecologicOther solid neoplasmThoracic

30 enrolled

Adenocarcinoma of Lung, Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Carcinoma, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04990037 2023-06-29

CAPAFOUR

25 enrolled

Gastrointestinal

Adenocarcinoma, Carcinoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT05153408 2023-06-18

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

20 enrolled

NCT04363242 2023-04-12

A Study to Find the MTD of SYN125 in People With Solid Tumors and the MTD of SYN125 With a Fixed Dose of SYN004 in People in Patients With Epithelial Cancers With EGFR Expressions

22 enrolled

Carcinoma

NCT03420742 2023-01-27

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

24 enrolled 17 charts

Carcinoma, Lung Neoplasms, Neoplasms

NCT02437916 2022-11-08

Safety Study of AMG 228 to Treat Solid Tumors

DermatologicGastrointestinalHead & NeckThoracic

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Melanoma, Neoplasms, Colorectal Neoplasms

NCT04596033 2022-07-15

TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

49 enrolled

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT03852511 2022-06-24

FORTITUDE

28 enrolled

Carcinoma, Neoplasm Metastasis, Virus Diseases

NCT03985072 2022-02-24

Study With Andes-1537 in Patients With Specific Types of Advanced Solid Tumor

GastrointestinalGynecologic

67 enrolled

Carcinoma, Uterine Cervical Neoplasms, Gallbladder Neoplasms, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02636036 2021-11-09

SPICE

GastrointestinalHead & Neck

51 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Neoplasm Metastasis, Colorectal Neoplasms

NCT01353625 2021-10-05

Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

CNSGenitourinaryHead & NeckLymphoidOther hematologic neoplasmPlasma cell

118 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Glioblastoma, Leukemia, Lymphoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Prostatic Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse

NCT04419623 2021-05-12

A Study of TL-895 With Standard Available Treatment Versus Standard Available Treatment for the Treatment of COVID-19 in Patients With Cancer

Other hematologic neoplasm

7 enrolled

COVID-19, Carcinoma, Neoplasms, Hematologic Neoplasms

NCT02029690 2020-09-25

TRAP

CNSDermatologicGastrointestinal

85 enrolled

Uveal Melanoma, Carcinoma, Glioma, Carcinoma, Hepatocellular

NCT01999972 2020-09-24

A Phase 1b Study Of Axitinib In Combination With Crizotinib In Patients With Advanced Solid Tumors

50 enrolled 29 charts

Carcinoma

NCT02507544 2020-05-21

A Safety and Pharmacokinetic Study of TRX-818 Administered Orally to Patients With Advanced Cancer

36 enrolled

Carcinoma, Neoplasms

NCT01587703 2020-03-16

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK525762 in Subjects With NUT Midline Carcinoma (NMC) and Other Cancers

196 enrolled 78 charts

CNSPlasma cellThoracic

Carcinoma, Multiple Myeloma, Neoplasms, Neuroblastoma, Small Cell Lung Carcinoma

NCT00097903 2020-03-12

Trial of Oral Karenitecin in Patients With Solid Tumors and Lung Cancer

32 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT02529995 2020-02-11

AURAChinaPK

31 enrolled 22 charts

Carcinoma

NCT01295827 2019-12-13

KEYNOTE-001

1,260 enrolled 45 charts

Dermatologic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Melanoma, Neoplasm Metastasis, Neoplasms

NCT00862355 2019-05-03

Bioequivalence Study of SPARC147609 in Patients With Ovarian Cancer

24 enrolled

Gynecologic

Carcinoma, Ovarian Neoplasms

NCT00403052 2019-04-16

A Study of 1018 Immunostimulatory Sequence (ISS) Administered With Irinotecan and Cetuximab to Treat Patients With Previously Treated Metastatic Colorectal Cancer

Gastrointestinal

Carcinoma, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03908840 2019-04-09

Open-label Multicenter Phase 1 Study of TBI 302 as Second-Line Therapy in Patients With Hepatocellular Carcinoma

12 enrolled

Gastrointestinal

Carcinoma, Carcinoma, Hepatocellular, Neoplasms

NCT02703298 2019-03-28

Safety and Pharmacokinetic Study of TRX-818 in Asian Solid Tumor Patients

19 enrolled

Carcinoma, Neoplasms

NCT02454478 2019-03-19

Study of Lenvatinib in Combination With Everolimus in Participants With Unresectable Advanced or Metastatic Renal Cell Carcinoma (RCC)

7 enrolled 17 charts

Genitourinary

Carcinoma, Carcinoma, Renal Cell

NCT00726583 2018-05-17

Phase I Trial of Oral PX-866