Clinical Trials

CNSDermatologicGastrointestinalGenitourinarySarcoma

48 enrolled

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT05559879 2026-04-15

Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma

Phase 1/2 Recruiting

37 enrolled

Gynecologic

Carcinoma, Uterine Neoplasms, Endometrial Neoplasms

NCT06532279 2026-04-03

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

98 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Stomatitis

NCT07257094 2026-03-31

Nasal Reconstruction FACE-Q : French Validation of the Nasal Reconstruction FACE-Q Questionnaire for Reconstruction/Rehabilitation Following Nasal Skin Cancer

346 enrolled

Dermatologic

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT07400263 2026-03-30

Evaluation of an EpCAM-Targeted Radiotracer in Epithelial Tumors

Phase EARLY_PHASE1 Recruiting

Carcinoma

NCT05065736 2026-03-19

Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer

4 enrolled

Adenocarcinoma, Carcinoma, Neoplasm Metastasis, Neoplasms

NCT06128343 2026-03-19

BACAP-2

1,500 enrolled

Adenocarcinoma, Carcinoma, Neoplasms

NCT06205836 2026-03-17

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

44 enrolled

Adenocarcinoma, Carcinoma, Colorectal Neoplasms

NCT06456411 2026-03-10

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

410 enrolled

BreastGenitourinary

Breast Neoplasms, Carcinoma, Carcinoma, Renal Cell

NCT06868433 2026-03-04

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Recurrence

NCT06806930 2026-03-03

Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)

90 enrolled

Breast

Breast Neoplasms, Carcinoma, Neoplasms

NCT07408635 2026-02-13

IBI363 (PD-1/IL-2α-bias) in Combination With Chemotherapy as Neoadjuvant Therapy in Initially Unresectable Stage III Non-Small Cell Lung Cancer

43 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT06027086 2026-02-12

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

Phase 1/2 Recruiting

27 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma

NCT06636734 2026-02-11

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

28 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00349830 2026-02-10

Novel Serum Markers for Monitoring Response to Anti-Cancer Therapy

2,000 enrolled

Adenocarcinoma, Carcinoma, Neoplasms

NCT06612827 2025-12-24

OCAPI

20 enrolled

Carcinoma

NCT05917106 2025-12-11

Renal Cancer Monitoring Based on ctDNA Methylomics: A Prospective Cohort Study (MEMORY Study)

450 enrolled

Genitourinary

Carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms

NCT06564623 2025-12-05

Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC)

25 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Biliary Tract Neoplasms, Carcinoma

NCT06676527 2025-12-05

Vorolanib in the Second-line Treatment of Patients With Unresectable or Metastatic Renal Cell Carcinoma

39 enrolled

Genitourinary

Urogenital Diseases, Carcinoma, Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Neoplasms, Urogenital Neoplasms, Urologic Diseases, Urologic Neoplasms, Female Urogenital Diseases, Male Urogenital Diseases

NCT06001658 2025-12-03

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

27 enrolled

Biliary Tract Neoplasms, Carcinoma

NCT06782932 2025-12-03

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Phase 1/2 Recruiting

38 enrolled

Adenocarcinoma, Carcinoma, Pancreatic Neoplasms

NCT06941857 2025-12-03

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

20 enrolled

Carcinoma, Pancreatic Neoplasms

NCT07252323 2025-11-26

A Single-arm Phase II Clinical Study Investigating the Safety and Efficacy of Carbon Ion Radiotherapy in Patients With Hepatocellular Carcinoma Previously Treated With Transarterial Radioembolization (TARE)

48 enrolled

Carcinoma, Carcinoma, Hepatocellular

NCT07246668 2025-11-24

A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

52 enrolled

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT05977998 2025-11-19

A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology

Carcinoma

NCT06356272 2025-11-05

Oropharynx (OPX) Biomarker Trial

440 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Head and Neck Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms, Thyroid Neoplasms

NCT05541016 2025-11-04

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

455 enrolled

Carcinoma, Oropharyngeal Neoplasms

NCT06445114 2025-11-04

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

50 enrolled

Phase EARLY_PHASE1 Recruiting

Carcinoma, Oropharyngeal Neoplasms

NCT06914999 2025-10-22

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

20 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Oropharyngeal Neoplasms

NCT07145801 2025-10-07

TARE

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT06096688 2025-09-04

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

GastrointestinalGynecologic

1,120 enrolled

Carcinoma, Neoplastic Syndromes, Hereditary, Polyps, Colorectal Neoplasms, Endometrial Neoplasms

NCT06683846 2025-08-24

Ivonescimab in the Treatment of Multiple Advanced Tumors

CNSDermatologicEndocrineGenitourinarySarcoma

400 enrolled

Urachal cancer, Carcinoma, Carcinoma, Basal Cell, Carcinoma, Transitional Cell, Kidney Neoplasms, Paget Disease, Extramammary, Paraganglioma, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rhabdomyosarcoma, Sarcoma, Angiomyolipoma, Carcinoma, Neuroendocrine, Perivascular Epithelioid Cell Neoplasms

NCT05457595 2025-08-06

CYCLOPS

55 enrolled

Gynecologic

Carcinoma, Ovarian Neoplasms, Recurrence, Vulvar Neoplasms

NCT03370406 2025-06-15

Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

Carcinoma, Carcinoma, Squamous Cell

NCT06279143 2025-05-20

dOCT-pBCC

210 enrolled

Dermatologic

Carcinoma, Carcinoma, Basal Cell, Eyelid Diseases, Eyelid Neoplasms, Hypersensitivity, Neoplasms, Glandular and Epithelial, Recurrence, Skin Diseases, Skin Neoplasms

NCT06358222 2025-05-18

Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan

200 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lymphatic Metastasis

NCT06969534 2025-05-15

Safety and Efficacy of Pucotenlimab in pLECC

33 enrolled

Carcinoma

NCT06950814 2025-04-30

Prognostic Impact of Adjuvant Therapy in Primary Hepatic Sarcomatoid Carcinoma

50 enrolled

Carcinoma, Liver Neoplasms

NCT06833229 2025-04-11

FDG Immun Comb

200 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT06662058 2025-04-10

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

118 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT05463757 2025-04-04

Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study

80 enrolled

Dermatologic

Basal Cell Nevus Syndrome, Carcinoma, Carcinoma, Basal Cell, Skin Neoplasms, Neoplasms, Basal Cell

NCT05297734 2025-03-19

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer