Announcements Trials
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Phase

Phase 2 5Phase 1 2Phase NA 1Phase 4 1

Status

Terminated 3Completed 2

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 5Thoracic 1Sarcoma 1Plasma cell 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Breast Neoplasms 867Carcinoma, Non-Small-Cell Lung 637Prostatic Neoplasms 516Multiple Myeloma 441Neoplasms 425Leukemia, Myeloid, Acute 377Lymphoma 356Leukemia 335Melanoma 333Neoplasm Metastasis 321Lung Neoplasms 308Lymphoma, Non-Hodgkin 302Leukemia, Lymphocytic, Chronic, B-Cell 301Colorectal Neoplasms 281Ovarian Neoplasms 264Pancreatic Neoplasms 249Recurrence 240Precursor Cell Lymphoblastic Leukemia-Lymphoma 239Myelodysplastic Syndromes 233Glioblastoma 212Hodgkin Disease 201Lymphoma, Large B-Cell, Diffuse 197Lymphoma, Follicular 195Brain Neoplasms 194Carcinoma, Renal Cell 189Head and Neck Neoplasms 187Squamous Cell Carcinoma of Head and Neck 186Lymphoma, Mantle-Cell 171Sarcoma 158Fallopian Tube Neoplasms 139

Interventions

Doxorubicin 2Trastuzumab 1Reverse Transcriptase Polymerase Chain Reaction 1Paclitaxel 1Metformin 1Mass Spectrometry 1Lisinopril 1Lapatinib 1Gene Expression Profiling 1Fluorophotometry 1Cyclophosphamide 1Chemotherapy, Adjuvant 1Carvedilol 1Atorvastatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 2 × Has results × Cardiotoxicity × Clear all
NCT03862131 2025-07-29

PROACT

Washington University School of Medicine

Phase 2 Terminated
49 enrolled 12 charts
BreastLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

Breast Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Sarcoma, Neoplasms, Plasma Cell, Cardiotoxicity

NCT00436566 2022-08-05

Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

Mayo Clinic

Phase 2 Completed
122 enrolled 22 charts
Breast

Breast Neoplasms, Breast Neoplasms, Male, Cardiotoxicity

NCT01009918 2021-03-30

Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab

University of South Florida

Phase 2 Completed
468 enrolled 16 charts
Breast

Breast Neoplasms, Breast Neoplasms, Male, Cardiotoxicity

NCT02472353 2019-10-16

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Avera McKennan Hospital & University Health Center

Phase 2 Terminated
30 enrolled 10 charts
Breast

Breast Neoplasms, Neoplasms, Cardiotoxicity

NCT02674204 2019-05-15

STOP

Cedars-Sinai Medical Center

Phase 2 Terminated
2 enrolled 7 charts
Breast

Breast Neoplasms, Heart Diseases, Cardiotoxicity

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