Announcements Trials
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Phase

Phase 3 4Phase 1 1

Status

Completed 5Terminated 2Recruiting 1

Sponsor Class

NETWORK 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 3Sarcoma 1Other hematologic neoplasm 1

Conditions

Sarcoma 6Cardiotoxicity 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Lymphoma 3Neuroblastoma 2Leukemia 2Vomiting 1Unspecified Adult Solid Tumor, Protocol Specific 1Sarcoma, Synovial 1Sarcoma, Ewing 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Recurrence 1Osteosarcoma 1Neurofibrosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Nausea 1Lymphoma, Large-Cell, Anaplastic 1Localized Extraskeletal Ewing Sarcoma 1Liposarcoma 1Leiomyosarcoma 1Histiocytoma, Malignant Fibrous 1Hemangiosarcoma 1Fibrosarcoma 1Extravasations of Anthracycline Anti-cancer Agents 1Extravasation 1Drug-Related Side Effects and Adverse Reactions 1Dermatofibrosarcoma 1Degradation of Top2b and Top2a in Human by Dexrazoxane 1Central Nervous System Neoplasms 1

Interventions

Doxorubicin 11Razoxane 5Dexrazoxane 5Electrocardiography 4Echocardiography 4Cyclophosphamide 4Vincristine 3Trastuzumab 3Granulocyte Colony-Stimulating Factor 3Filgrastim 3Exercise 3Etoposide 3Carvedilol 3Radiotherapy 2Prednisone 2Methotrexate 2Magnetic Resonance Spectroscopy 2Bleomycin 2salicylhydroxamic acid 1oblimersen 1hydrocortisone hemisuccinate 1dapagliflozin 1Vascular Stiffness 1VAP-cyclo protocol 1Tablets 1Silymarin 1Reverse Transcriptase Polymerase Chain Reaction 1Resistance Training 1Pulse Wave Analysis 1Palliative Care 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Cardiotoxicity × Dexrazoxane × Clear all
NCT00003937 2014-08-05

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Children's Oncology Group

Phase 3 Completed
253 enrolled
Sarcoma

Sarcoma, Cardiotoxicity

NCT00005578 2014-07-24

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Children's Oncology Group

Phase 3 Completed
219 enrolled
Lymphoid

Lymphoma, Cardiotoxicity

NCT00002827 2013-08-26

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Children's Oncology Group

Phase 3 Completed
294 enrolled
Lymphoid

Lymphoma, Cardiotoxicity

NCT01230983 2013-06-06

T-Cell #4

Children's Oncology Group

Phase 3 Completed
573 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Cardiotoxicity

NCT00039481 2013-01-17

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
15 enrolled

Cardiotoxicity

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