Announcements Trials
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Phase

Phase 3 5Phase 1 1

Status

Completed 5Terminated 1

Sponsor Class

NETWORK 4NIH 2

Study Type

Interventional 6

Sponsor

Cancer Type

Lymphoid 3Sarcoma 1Other hematologic neoplasm 1Breast 1

Conditions

Cardiotoxicity 6Sarcoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma 3Neuroblastoma 2Lymphoma, Large-Cell, Anaplastic 2Leukemia, Myeloid, Acute 2Leukemia, Biphenotypic, Acute 2Ganglioneuroblastoma 2Burkitt Lymphoma 2Blast Crisis 2Sezary Syndrome 1Sarcoma, Synovial 1Sarcoma, Myeloid 1Rhabdoid Tumor 1Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Pleuropulmonary blastoma 1PRETEXT I Hepatoblastoma 1Osteosarcoma 1Neurofibrosarcoma 1Myeloproliferative Disorders 1Mycosis Fungoides 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Extranodal NK-T-Cell 1Localized Extraskeletal Ewing Sarcoma 1Liposarcoma 1Leukemia, Lymphocytic, Chronic, B-Cell 1

Interventions

Doxorubicin 15Exercise 9Cyclophosphamide 9Dexrazoxane 8Razoxane 6Carvedilol 6Vincristine 4Trastuzumab 4Radiotherapy 4Filgrastim 4Docetaxel 4Methotrexate 3Granulocyte Colony-Stimulating Factor 3Etoposide 3Echocardiography 3Atorvastatin 3salicylhydroxamic acid 2sacubitril and valsartan sodium hydrate drug combination 2empagliflozin 2dapagliflozin 2Tablets 2Silymarin 2Prednisone 2Paclitaxel 2Neoadjuvant Therapy 2Leucovorin 2Ivabradine 2High-Intensity Interval Training 2Epirubicin 2Electrocardiography 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Interventional × Cardiotoxicity × Razoxane × Clear all
NCT00003937 2014-08-05

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Children's Oncology Group

Phase 3 Completed
253 enrolled
Sarcoma

Sarcoma, Cardiotoxicity

NCT00005578 2014-07-24

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Children's Oncology Group

Phase 3 Completed
219 enrolled
Lymphoid

Lymphoma, Cardiotoxicity

NCT00002827 2013-08-26

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Children's Oncology Group

Phase 3 Completed
294 enrolled
Lymphoid

Lymphoma, Cardiotoxicity

NCT01230983 2013-06-06

T-Cell #4

Children's Oncology Group

Phase 3 Completed
573 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Cardiotoxicity

NCT00039481 2013-01-17

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
15 enrolled

Cardiotoxicity

NCT00016276 2013-01-16

Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer

National Cancer Institute (NCI)

Phase 3 Terminated
396 enrolled
Breast

Breast Neoplasms, Inflammatory Breast Neoplasms, Cardiotoxicity

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