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Phase

Phase 3 1

Status

Active not recruiting 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Brain Neoplasms 20Breast Neoplasms 8Neoplasm Metastasis 4Central Nervous System Neoplasms 4Radiation Injuries 3Neoplasms 3Glioma 3Glioblastoma 3Fatigue 3Unspecified Adult Solid Tumor, Protocol Specific 2Small Cell Lung Carcinoma 2Medulloblastoma 2Lung Neoplasms 2Gliosarcoma 2Ependymoma 2Depression 2Craniopharyngioma 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms, Male 2Triple Negative Breast Neoplasms 1Rectal Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Pinealoma 1Oligodendroglioma 1Neurotoxicity Syndromes 1Neuroectodermal Tumors, Primitive 1Neoplasms, Plasma Cell 1Neoplasms, Germ Cell and Embryonal 1Meningioma 1

Interventions

Specimen Handling 1Mental Status and Dementia Tests 1Memantine 1Magnetic Resonance Spectroscopy 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Central Nervous System Carcinoma × Mental Status and Dementia Tests × Clear all
NCT04939597 2025-12-22

A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor

Children's Oncology Group

Phase 3 Active not recruiting
192 enrolled
CNS

Central Nervous System Carcinoma

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