Clinical Trials Browser

Phase 1/2 × Has results × Central Nervous System Diseases × Clear all

NCT04971733 2025-06-10

A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease

Phase 1/2 Completed

8 enrolled 21 charts

CNSLymphoid

Alzheimer Disease, Central Nervous System Diseases, Lymphoma, Follicular

NCT01081223 2023-06-01

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

Phase 1/2 Completed

12 enrolled 11 charts

CNS

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT00924820 2020-12-31

A Pilot Study of Bevacizumab for Neoplastic Meningitis

Phase 1/2 Completed

20 enrolled 7 charts

CNS

Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Meningeal Carcinomatosis

NCT00050986 2020-09-22

Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma Multiforme

Phase 1/2 Completed

55 enrolled 6 charts

CNS

Brain Neoplasms, Central Nervous System Diseases, Glioblastoma

NCT01596127 2018-05-24

Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System

Phase 1/2 Terminated

4 enrolled 7 charts

CNSOther hematologic neoplasm

Central Nervous System Diseases, Leukemia, Meningeal Neoplasms, Meningeal Carcinomatosis