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Phase

Phase 1 2Phase 1/2 1

Status

Terminated 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1Lymphoid 1

Conditions

Multiple Myeloma 430Lymphoma, Large B-Cell, Diffuse 97Leukemia, Lymphocytic, Chronic, B-Cell 88Lymphoma, Follicular 81Recurrence 72Lymphoma 62Lymphoma, Mantle-Cell 59Neoplasms, Plasma Cell 58Lymphoma, B-Cell, Marginal Zone 47Lymphoma, Non-Hodgkin 46Leukemia, Myeloid, Acute 34Leukemia 32Neoplasms 24Myelodysplastic Syndromes 24Lymphoma, B-Cell 24Waldenstrom Macroglobulinemia 18Hodgkin Disease 18Smoldering Multiple Myeloma 17Lymphoma, T-Cell, Peripheral 16Burkitt Lymphoma 14Hematologic Diseases 13Lymphoma, T-Cell, Cutaneous 12Lymphoma, T-Cell 12Prostatic Neoplasms 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 11Sezary Syndrome 10Mycosis Fungoides 10Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma, Large-Cell, Anaplastic 9Leukemia, Myelomonocytic, Chronic 9

Interventions

Radiotherapy 122Temozolomide 110Carboplatin 53Filgrastim 46Vincristine 43Etoposide 39Cyclophosphamide 37Chemotherapy, Adjuvant 37Cisplatin 36Carmustine 32Irinotecan 27Peripheral Blood Stem Cell Transplantation 25Magnetic Resonance Spectroscopy 24Lomustine 22Thiotepa 21Methotrexate 20Granulocyte Colony-Stimulating Factor 18Procarbazine 16Bevacizumab 16Surgical Procedures, Operative 15O(6)-benzylguanine 14etoposide phosphate 13Drug Therapy 13Topotecan 12Paclitaxel 12Ifosfamide 12Thalidomide 11Radiation 11sargramostim 10Specimen Handling 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Central Nervous System Neoplasms × Lenalidomide × Clear all
NCT04446962 2025-09-25

LOC-R01

Institut Curie

Phase 1/2 Active not recruiting
118 enrolled
CNSLymphoid

Lymphoma, Neurologic Manifestations, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms

NCT03050450 2021-04-05

Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors

Johns Hopkins All Children's Hospital

Phase 1 Terminated
8 enrolled 10 charts
CNS

Central Nervous System Neoplasms

NCT00036894 2015-04-30

CC-5013 in Treating Patients With Recurrent Glioma

National Cancer Institute (NCI)

Phase 1 Completed
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

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