Announcements Trials
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Phase

Phase 1 2Phase 1/2 1

Status

Completed 3

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 2

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 32Myelodysplastic Syndromes 30Leukemia, Myeloid, Acute 30Multiple Myeloma 24Lymphoma, Non-Hodgkin 24Hodgkin Disease 24Lymphoma 21Leukemia 21Graft vs Host Disease 21Leukemia, Lymphocytic, Chronic, B-Cell 20Leukemia, Myelogenous, Chronic, BCR-ABL Positive 16Myeloproliferative Disorders 15Lymphoma, Mantle-Cell 15Neoplasms 14Tuberous Sclerosis 13Lymphoma, Large B-Cell, Diffuse 13Hematologic Neoplasms 12Burkitt Lymphoma 12Primary Myelofibrosis 11Lymphoma, Follicular 11Breast Neoplasms 11Waldenstrom Macroglobulinemia 10Sarcoma 10Recurrence 10Neoplasms, Plasma Cell 10Neoplasm Metastasis 10Lymphoma, B-Cell, Marginal Zone 10Leukemia, Myelomonocytic, Chronic 10Prostatic Neoplasms 9Lymphangioleiomyomatosis 9

Interventions

Temozolomide 64Radiotherapy 53Filgrastim 28Carboplatin 24Etoposide 20Irinotecan 17Vincristine 16Cyclophosphamide 16Cisplatin 15Carmustine 14Peripheral Blood Stem Cell Transplantation 13Magnetic Resonance Spectroscopy 12Bevacizumab 12Thiotepa 11Thalidomide 11Chemotherapy, Adjuvant 11Methotrexate 10Paclitaxel 9Granulocyte Colony-Stimulating Factor 9etoposide phosphate 8Surgical Procedures, Operative 8Procarbazine 8Ifosfamide 8sargramostim 7Topotecan 7O(6)-benzylguanine 7Lomustine 7Busulfan 7Radiation 6Melphalan 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Central Nervous System Neoplasms × Sirolimus × Clear all
NCT00047073 2020-08-03

Sirolimus in Treating Patients With Glioblastoma Multiforme

Jonsson Comprehensive Cancer Center

Phase 1/2 Completed
13 enrolled
CNSSarcoma

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00509431 2020-07-31

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

Jonsson Comprehensive Cancer Center

Phase 1 Completed
19 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01135563 2019-09-20

Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours

The Hospital for Sick Children

Phase 1 Completed
14 enrolled
CNS

Recurrence, Central Nervous System Neoplasms

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