Clinical Trials

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00387400 2023-08-04

Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

32 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00876993 2023-07-03

Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

26 enrolled 16 charts

Central Nervous System Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00275002 2022-02-11

O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors

41 enrolled 9 charts

Central Nervous System Neoplasms

NCT00112502 2021-10-18

Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme

178 enrolled 23 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00049361 2021-09-09

Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases

Brain Neoplasms, Central Nervous System Neoplasms

NCT01217437 2021-07-23

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

108 enrolled 14 charts

Medulloblastoma, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive

NCT02116777 2021-03-26

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

40 enrolled 32 charts

Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT00905060 2021-03-24

HeatShock

70 enrolled 12 charts

Central Nervous System Neoplasms

NCT00033280 2020-10-22

Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas

42 enrolled

Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01013285 2020-09-21

Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

70 enrolled 18 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00601289 2020-07-31

Temozolomide in Treating Patients With Invasive Pituitary Tumors

Phase 2 Withdrawn

CNSEndocrine

Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Pituitary Neoplasms, Prolactinoma, Central Nervous System Neoplasms, Growth Hormone-Secreting Pituitary Adenoma

NCT00756106 2020-05-13

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

Phase NA Terminated

15 enrolled 6 charts

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00275067 2020-02-25

Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery

Phase 1/2 Unknown

50 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

122 enrolled 11 charts

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00869401 2020-02-13

Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

217 enrolled 12 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004259 2019-09-12

Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas

Phase 3 Completed

230 enrolled 14 charts

Astrocytoma, Glioma, Central Nervous System Neoplasms

NCT00486603 2019-07-10

Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme

92 enrolled 18 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01480050 2019-05-22

Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

28 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00915694 2019-04-23

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

Phase 1 Terminated

15 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01164189 2019-02-28

TAVAREC

155 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00313729 2019-02-07

Temozolomide in Treating Patients With Low-Grade Glioma

120 enrolled 8 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00400816 2018-09-18

Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma

29 enrolled

Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01019434 2018-07-09

Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

111 enrolled

Glioblastoma, Central Nervous System Neoplasms

NCT00003176 2018-06-27

Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma

82 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006025 2018-06-27

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00027625 2018-06-27

Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00238277 2018-06-27

Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme

Phase 2 Terminated

15 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00770471 2018-06-27

ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

24 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006358 2018-06-26

Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor

44 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00077207 2018-05-16

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Phase NA Completed

66 enrolled 13 charts

Brain Neoplasms, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00974987 2018-04-25

Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

32 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00547131 2018-04-17

Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors

12 enrolled

Brain Neoplasms, Neoplasm Metastasis, Central Nervous System Neoplasms

NCT00068250 2018-02-07

Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

60 enrolled 10 charts

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT01390571 2018-02-05

Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma

34 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00619112 2018-01-31

Temozolomide in Treating Patients With Recurrent High-Grade Glioma

60 enrolled 9 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00109798 2017-09-19

Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma

Phase NA Withdrawn

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT00086879 2017-07-27

Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme

110 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00047294 2017-07-11

Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme