Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Brain Neoplasms 4Sarcoma 3Neoplasms 3Recurrence 2Ovarian Neoplasms 2Neoplasm Metastasis 2Nasopharyngeal Carcinoma 2Medulloblastoma 2Glioblastoma 2Central Nervous System Neoplasms 2Breast Neoplasms 2Astrocytoma 2Urologic Neoplasms 1Thyroid Neoplasms 1Spinal Cord Neoplasms 1Solid Tumors 1Solid Tumor Malignancies 1Soft Tissue Neoplasms 1Pharyngeal Neoplasms 1Osteosarcoma 1Optic Nerve Glioma 1Neurofibromatosis 2 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroectodermal Tumors 1Neuroblastoma 1Neoplasms, Mesothelial 1Myelodysplastic Syndromes 1Multiple Acyl Coenzyme A Dehydrogenase Deficiency 1Mouth Neoplasms 1

Interventions

Temozolomide 30Radiotherapy 23Filgrastim 12Carmustine 12Irinotecan 11Carboplatin 11Chemotherapy, Adjuvant 9O(6)-benzylguanine 8Etoposide 7Surgical Procedures, Operative 6Magnetic Resonance Spectroscopy 6Vincristine 5Peripheral Blood Stem Cell Transplantation 5Granulocyte Colony-Stimulating Factor 5Cyclophosphamide 5sargramostim 4motexafin gadolinium 4Topotecan 4Thiotepa 4Paclitaxel 4Melphalan 4Gene Expression Profiling 4Gemcitabine 4Drug Therapy 4Busulfan 4temsirolimus 3etoposide phosphate 3Specimen Handling 3Mass Spectrometry 3Imatinib Mesylate 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Central Nervous System Neoplasms × Valproic Acid × Clear all
NCT01204450 2016-12-23

Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

UNC Lineberger Comprehensive Cancer Center

Phase 1 Terminated
7 enrolled
CNSSarcoma

Neuroblastoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Children's Oncology Group

Phase 1 Completed
26 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

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