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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Ovarian Neoplasms 40Breast Neoplasms 12Prostatic Neoplasms 11Fallopian Tube Neoplasms 10Pancreatic Neoplasms 7Neoplasms 7Endometrial Neoplasms 7Glioblastoma 6Neoplasm Metastasis 5Carcinoma, Ovarian Epithelial 5Triple Negative Breast Neoplasms 4Lung Neoplasms 4Glioma 4Small Cell Lung Carcinoma 3Mesothelioma 3Cystadenocarcinoma, Serous 3Cholangiocarcinoma 3Uterine Neoplasms 2Uterine Cervical Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Recurrence 2Mesothelioma, Malignant 2Head and Neck Neoplasms 2Colorectal Neoplasms 2Carcinoma, Renal Cell 2Carcinoma 2Brain Neoplasms 2Biliary Tract Neoplasms 2Uveal Melanoma 1

Interventions

Temozolomide 64Radiotherapy 53Filgrastim 28Carboplatin 24Etoposide 20Irinotecan 17Vincristine 16Cyclophosphamide 16Cisplatin 15Carmustine 14Peripheral Blood Stem Cell Transplantation 13Magnetic Resonance Spectroscopy 12Bevacizumab 12Thiotepa 11Thalidomide 11Chemotherapy, Adjuvant 11Methotrexate 10Paclitaxel 9Granulocyte Colony-Stimulating Factor 9etoposide phosphate 8Surgical Procedures, Operative 8Procarbazine 8Ifosfamide 8sargramostim 7Topotecan 7O(6)-benzylguanine 7Lomustine 7Busulfan 7Radiation 6Melphalan 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Central Nervous System Neoplasms × niraparib × Clear all
NCT04992013 2026-06-01

Niraparib in Tumors Metastatic to the CNS

Massachusetts General Hospital

Phase 2 Active not recruiting
20 enrolled
CNS

Neoplasm Metastasis, Central Nervous System Neoplasms

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