Clinical Trials Browser

Phase 1 × Withdrawn × Central Nervous System Neoplasms × Clear all

NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

Phase 1 Withdrawn

CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT05720624 2025-10-22

Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation

Phase 1 Withdrawn

CNS

Central Nervous System Neoplasms

NCT04500548 2025-09-10

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Phase 1 Withdrawn

CNSGastrointestinalLymphoidOther hematologic neoplasm

Turcot syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Lymphoma, Neuroblastoma, Xeroderma Pigmentosum, Central Nervous System Neoplasms, Hematologic Neoplasms

NCT03990597 2024-10-09

StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord

Phase 1 Withdrawn

CNS

Ependymoma, Glioma, Medulloblastoma, Pinealoma, Central Nervous System Neoplasms

NCT05952687 2024-03-27

Trial of Idasanutlin and Selinexor Therapy for Children With Progressive/Relapsed AT/RT or Extra-CNS Malignant Rhabdoid Tumors

Phase 1 Withdrawn

CNS

Central Nervous System Neoplasms, Rhabdoid Tumor

NCT01052363 2017-02-09

OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas

Phase 1 Withdrawn

CNS

Central Nervous System Neoplasms

NCT01320787 2014-10-23

18-F-Fluoroacetate as PET Imaging Agent

Phase 1 Withdrawn

BreastCNSGenitourinary

Brain Neoplasms, Breast Neoplasms, Prostatic Neoplasms, Central Nervous System Neoplasms

NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Phase 1 Withdrawn

CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating