Announcements Trials
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Phase

Phase 3 2Phase 2 1

Status

Completed 84Terminated 10Withdrawn 4Unknown 3Recruiting 3Active not recruiting 3

Sponsor Class

OTHER 10NIH 7INDUSTRY 7NETWORK 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Breast Neoplasms 19Multiple Myeloma 16Prostatic Neoplasms 14Carcinoma, Non-Small-Cell Lung 12Neoplasms 10Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma 9Leukemia, Myeloid, Acute 7Lung Neoplasms 6Leukemia, Biphenotypic, Acute 6Squamous Cell Carcinoma of Head and Neck 5Neuroblastoma 5Medulloblastoma 5Lymphoma, Mantle-Cell 5Leukemia 5Hodgkin Disease 5Ependymoma 5Colorectal Neoplasms 5Oropharyngeal Neoplasms 4Neoplasm Metastasis 4Myelodysplastic Syndromes 4Leukemia, Myeloid, Chronic-Phase 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Burkitt Lymphoma 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Oligodendroglioma 3Melanoma 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hematologic Neoplasms 3Glioma 3

Interventions

Temozolomide 2larotrectinib 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1DNA Methylation 1Chemotherapy, Adjuvant 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Active not recruiting × NETWORK × Central Nervous System Neoplasms × Clear all
NCT03834961 2025-12-02

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Children's Oncology Group

Phase 2 Active not recruiting
33 enrolled 18 charts
CNS

Central Nervous System Neoplasms

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Eastern Cooperative Oncology Group

Phase 3 Active not recruiting
540 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00626990 2023-09-11

CATNON

European Organisation for Research and Treatment of Cancer - EORTC

Phase 3 Active not recruiting
751 enrolled 18 charts
CNS

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

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