Clinical Trials

155 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT06150547 2025-08-12

A Study of Metabolic Agents Following Brain Radiation

5 enrolled

Central Nervous System Neoplasms

NCT04743310 2025-06-13

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

50 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Neuroma, Acoustic, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00328458 2025-05-02

EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients

39 enrolled

CNSHead & Neck

Head and Neck Neoplasms, Central Nervous System Neoplasms

NCT00329589 2025-05-02

A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients

CNSGynecologicHead & Neck

54 enrolled

Brain Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Central Nervous System Neoplasms

NCT04479514 2025-05-01

Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy

14 enrolled 6 charts

Dermatitis, Neoplasms, Central Nervous System Neoplasms

NCT06168825 2025-02-27

MOM

BreastCNSDermatologicGastrointestinalHead & NeckOther hematologic neoplasmThoracic

40 enrolled

Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms, Central Nervous System Neoplasms, Hematologic Neoplasms

NCT01595126 2025-02-19

Longitudinal Study of Biomarkers

100 enrolled

Central Nervous System Neoplasms

NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

21 enrolled

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT04539574 2025-01-08

An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors

50 enrolled 6 charts

Phase EARLY_PHASE1 Completed

Glioma, Neoplasm Metastasis, Central Nervous System Neoplasms

NCT04217694 2024-11-21

Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

18 enrolled

Central Nervous System Neoplasms

NCT03071913 2024-09-27

Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery

54 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT03052738 2024-08-29

Medical Marijuana in the Pediatric Central Nervous System Tumor Population

19 enrolled

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

68 enrolled

CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT04296617 2024-05-17

Brain Imaging Changes Following Proton Therapy for Pediatric Primary Central Nervous System and Base of Skull Tumors

36 enrolled

Central Nervous System Neoplasms

NCT00884598 2024-05-10

CIRAB

19 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Central Nervous System Neoplasms

NCT03055364 2024-05-10

Cognitive Function After Treatment of Primary CNS Malignancy

129 enrolled

Central Nervous System Neoplasms

NCT03206021 2024-04-05

COZMOS

31 enrolled

Ependymoma, Central Nervous System Neoplasms

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

78 enrolled 11 charts

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT04276194 2024-03-21

Vertebral Body Sparing Craniospinal Irradiation for Pediatric Patients With Cancer of the Central Nervous System

10 enrolled

Central Nervous System Neoplasms

NCT03012620 2024-02-28

AcSé

CNSEndocrineGynecologicHead & NeckLymphoidSarcoma

334 enrolled

Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Carcinoma, Neuroendocrine, Lymphoma, Extranodal NK-T-Cell

NCT01505569 2024-02-26

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

44 enrolled

Brain Neoplasms, Carcinoma, Renal Cell, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Rhabdoid Tumor

NCT00085202 2024-02-08

Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

Phase 3 Completed

416 enrolled 16 charts

Central Nervous System Neoplasms, Rhabdoid Tumor

NCT03188354 2024-01-05

Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma

3 enrolled

CNSLymphoid

Lymphoma, Non-Hodgkin, Central Nervous System Neoplasms

NCT00002965 2023-12-22

Interferon Alfa in Treating Patients With Recurrent Unresectable Meningiomas and Malignant Meningiomas

16 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT03565367 2023-12-21

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

9 enrolled 6 charts

Central Nervous System Neoplasms

NCT00588523 2023-10-27

Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma

60 enrolled 9 charts

Central Nervous System Neoplasms

NCT02793466 2023-09-22

Durvalumab in Pediatric and Adolescent Patients

15 enrolled

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT04456140 2023-07-24

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

BreastCNSGastrointestinalHead & Neck

230 enrolled

Brain Neoplasms, Breast Neoplasms, Digestive System Neoplasms, Head and Neck Neoplasms, Neoplasms, Unknown Primary, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT00876993 2023-07-03

Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

26 enrolled 16 charts

Central Nervous System Neoplasms

NCT00187226 2023-05-31

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

361 enrolled 11 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT03696355 2023-01-18

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

27 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms

NCT04657315 2023-01-18

MSC11FCD-GBM

Phase 1/2 Completed

10 enrolled

Brain Neoplasms, Glioblastoma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms, Gliosarcoma

NCT05641636 2022-12-07

Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors

60 enrolled

Central Nervous System Neoplasms, Dyslipidemias

NCT04334239 2022-08-23

WiZen

BreastCNSGastrointestinalGenitourinaryGynecologicHead & Neck

670,000 enrolled

Breast Neoplasms, Carcinoma, Bronchogenic, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Central Nervous System Neoplasms, Endometrial Neoplasms

NCT01067196 2022-06-10

CN01

500 enrolled

Neoplasms, Central Nervous System Neoplasms

NCT00105560 2021-12-28

Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma

59 enrolled 26 charts

Central Nervous System Neoplasms

NCT00112502 2021-10-18

Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme

178 enrolled 23 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00752323 2021-09-17

Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma

73 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00049361 2021-09-09

Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases

Brain Neoplasms, Central Nervous System Neoplasms

NCT00070161 2021-09-09

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

68 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Radiation Injuries, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00079092 2021-09-09

Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma

18 enrolled

Phase EARLY_PHASE1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00424242 2021-09-08

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

15 enrolled

CNSDermatologicLymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cell

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Brain Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Polycythemia Vera, Precancerous Conditions, Sezary Syndrome, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Central Nervous System Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis, Meningeal Carcinomatosis, Intraocular Lymphoma

NCT04351035 2021-09-08

National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry

4,303 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT01346267 2021-08-18

SCUSF1202

187 enrolled 5 charts

Astrocytoma, Meningioma, Nausea, Oligodendroglioma, Vomiting, Central Nervous System Neoplasms, Choroid Plexus Neoplasms

NCT01381718 2021-08-13

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

112 enrolled 16 charts

Fatigue, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00293423 2021-05-13

GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma

Phase 1/2 Completed

96 enrolled 19 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms

NCT00905060 2021-03-24

HeatShock

70 enrolled 12 charts