Clinical Trials

14 enrolled

Central Nervous System Neoplasms

NCT00788125 2023-07-14

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

7 enrolled 9 charts

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Burkitt Lymphoma, Carcinoma, Renal Cell, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Spinal Cord Neoplasms, Teratoma, Testicular Neoplasms, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Nephroma, Mesoblastic, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT00074165 2023-07-06

Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen

CNSClassical hematologyLymphoid

17 enrolled 7 charts

Lymphoma, Thrombocytopenia, Central Nervous System Neoplasms, Intraocular Lymphoma, Drug-Related Side Effects and Adverse Reactions

NCT00014443 2023-01-09

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

5 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01295697 2022-02-14

Study of EZN-2208 Pediatric Patients With Solid Tumors

32 enrolled

Central Nervous System Neoplasms

NCT00633958 2021-10-20

FLT

2 enrolled

Disease, Central Nervous System Neoplasms

NCT00031798 2021-09-09

Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors

Phase 3 Terminated

Astrocytoma, Brain Neoplasms, Depression, Ependymoma, Fatigue, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT01201850 2021-05-19

The Role of Bevacizumab in the Treatment of Radiation Necrosis in Children With Central Nervous System Tumors

7 enrolled 8 charts

Central Nervous System Neoplasms

NCT03050450 2021-04-05

Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors

8 enrolled 10 charts

Central Nervous System Neoplasms

NCT00006916 2020-10-26

Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

19 enrolled 4 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00726830 2020-09-24

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

CNSDermatologicLymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cell

1 enrolled 3 charts

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Pain, Polycythemia Vera, Precancerous Conditions, Sezary Syndrome, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Central Nervous System Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis, Intraocular Lymphoma

NCT00616642 2020-08-14

Rosiglitazone in Treating Patients With Pituitary Tumors

1 enrolled 4 charts

CNSEndocrine

Pituitary Neoplasms, Central Nervous System Neoplasms

NCT00756106 2020-05-13

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

15 enrolled 6 charts

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT03182257 2019-09-13

ONTRK

1 enrolled

Neoplasms, Central Nervous System Neoplasms

NCT01582152 2019-06-05

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

12 enrolled 7 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00243022 2019-04-30

Dietary, Herbal and Alternative Medicine in Glioblastoma Multiforme

12 enrolled 15 charts

Astrocytoma, Brain Edema, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00031590 2019-04-25

Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma

30 enrolled 5 charts

Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT00915694 2019-04-23

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

15 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00631137 2018-08-27

Testosterone Gel in Preventing Weakness Caused by Steroid Therapy in Men With Glioma

1 enrolled 2 charts

Astrocytoma, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00052715 2018-07-18

Poly-ICLC

31 enrolled 8 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00238277 2018-06-27

Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme

15 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00623077 2017-12-05

MT2004-30: Tomotherapy for Solid Tumors

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

23 enrolled

Familial ependymoma, Astrocytoma, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00003926 2017-11-29

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

CNSGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcoma

13 enrolled

Ovarian Germ Cell Cancer, Astrocytoma, Brain Neoplasms, Chordoma, Ependymoma, Glioma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Hepatoblastoma, Desmoplastic Small Round Cell Tumor

NCT02988726 2017-07-26

Antineoplaston Therapy in Treating Patients With Neurofibroma and Schwannoma

3 enrolled

Neurilemmoma, Neurofibroma, Central Nervous System Neoplasms

NCT00238173 2017-04-21

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

2 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma, Drug-Related Side Effects and Adverse Reactions

NCT00253721 2017-04-21

Melphalan With BBBD in Treating Patients With Brain Malignancies

21 enrolled

CNSLymphoid

Astrocytoma, Brain Neoplasms, Glioma, Lymphoma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms

NCT00436436 2017-03-28

O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

12 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00582608 2017-03-01

Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9

12 enrolled 6 charts

Neuroblastoma, Sarcoma, Central Nervous System Neoplasms

NCT01266070 2017-02-13

TKI 258 in Von Hippel-Lindau Syndrome (VHL)

6 enrolled 5 charts

von Hippel-Lindau Disease, Central Nervous System Neoplasms, Hemangioblastoma

NCT01204450 2016-12-23

Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

7 enrolled

Neuroblastoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT00952185 2015-06-08

Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers

CNSClassical hematologyDermatologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

9 enrolled

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Anemia, Aplastic, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Polycythemia Vera, Sezary Syndrome, Thrombocythemia, Essential, Virus Diseases, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Central Nervous System Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis, Intraocular Lymphoma

NCT00031577 2015-03-19

Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

11 enrolled

Central Nervous System Neoplasms

NCT00068770 2015-03-18

Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RT

35 enrolled 12 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00021229 2014-07-31

Imatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurrent Glioma

85 enrolled 17 charts

Astrocytoma, Central Nervous System Neoplasms

NCT00002947 2014-07-02

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

CNSDermatologicEndocrineGenitourinaryHead & NeckThoracic

35 enrolled

Uveal Melanoma, Carcinoma, Renal Cell, Vipoma, Glucagonoma, Head and Neck Neoplasms, Insulinoma, Adenoma, Islet Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Pheochromocytoma, Somatostatinoma, Carcinoma, Merkel Cell, Gastrinoma, Central Nervous System Neoplasms, Carcinoma, Islet Cell, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT01348607 2014-02-21

Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer Therapy

1 enrolled 5 charts

Fatigue, Sleep Wake Disorders, Central Nervous System Neoplasms

NCT00107471 2013-12-10

Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma

7 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT01233492 2013-10-08

Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme

36 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00005812 2013-05-14

Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

12 enrolled

Brain Neoplasms, Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT00512798 2012-10-02

Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma

47 enrolled 9 charts

CNSDermatologic

Brain Neoplasms, Melanoma, Central Nervous System Neoplasms

NCT00104936 2012-09-24

Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by Surgery

Phase 3 Terminated

9 enrolled