Clinical Trials

75 enrolled 17 charts

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT05194735 2025-11-10

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

GastrointestinalGynecologicThoracic

8 enrolled 12 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT02881554 2025-10-29

Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery

41 enrolled 14 charts

BreastGastrointestinalSarcoma

Carcinoma, Hepatocellular, Liver Neoplasms, Thrombosis, Cholangiocarcinoma

NCT02784795 2025-08-21

A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors

Phase 1 Terminated

94 enrolled 28 charts

Breast Neoplasms, Colonic Neoplasms, Sarcoma, Cholangiocarcinoma

NCT02807181 2025-05-09

SIRCCA

Phase 2/3 Terminated

89 enrolled 23 charts

Cholangiocarcinoma

NCT04383210 2025-04-03

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

54 enrolled 11 charts

Fibromatosis, Gingival, 2, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Uterine Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT04989218 2024-11-05

ICC

1 enrolled 11 charts

Cholangiocarcinoma

NCT05012397 2024-10-17

Milademetan in Advanced/Metastatic Solid Tumors

DermatologicEndocrineGastrointestinalGenitourinaryGynecologicSarcomaThoracic

40 enrolled 13 charts

Testicular Germ Cell Tumor, Adenocarcinoma of Lung, Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Adrenocortical Carcinoma, Cholangiocarcinoma

NCT04683939 2024-10-02

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors

13 enrolled 24 charts

Adenocarcinoma Of Esophagus, Biliary Tract Neoplasms, Esophageal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT03773302 2024-05-08

Phase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/Translocations

48 enrolled 26 charts

Cholangiocarcinoma

NCT04088188 2024-05-06

Gemcitabine and Cisplatin With Ivosidenib or Pemigatinib for the Treatment of Unresectable or Metastatic Cholangiocarcinoma

Phase 1 Terminated

8 enrolled 14 charts

Cholangiocarcinoma

NCT02452970 2024-04-24

EPIC

4 enrolled 6 charts

Cholangiocarcinoma

NCT04066491 2023-11-14

Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC

Phase 2/3 Terminated

309 enrolled 17 charts

Biliary Tract Neoplasms, Camurati-Engelmann Syndrome, Gallbladder Neoplasms, Cholangiocarcinoma

NCT04099888 2023-09-11

RELEASE

41 enrolled 17 charts

Bile Duct Neoplasms, Cholangiocarcinoma

NCT04566133 2023-08-21

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).

2 enrolled 9 charts

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma

NCT04644315 2023-08-07

ALpha-T

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

1 enrolled 5 charts

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Renal Cell, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Pancreatic Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT04276090 2023-07-25

Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

21 enrolled 14 charts

Bile Duct Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT02150967 2023-07-03

A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma

143 enrolled 25 charts 2 FDA

Cholangiocarcinoma

NCT04163900 2023-05-24

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

773 enrolled 15 charts

Adenocarcinoma, Biliary Tract Neoplasms, Digestive System Neoplasms, Neoplasm Metastasis, Neoplasms, Cholangiocarcinoma

NCT02393248 2023-01-06

Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)

BreastGastrointestinalGynecologicMyeloidPlasma cellThoracic

201 enrolled 71 charts

Breast Neoplasms, Lung Neoplasms, Multiple Myeloma, Myeloproliferative Disorders, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT02982720 2022-02-16

Evaluating Combination Immunotherapy for Advanced Cholangiocarcinoma With Pembrolizumab and PEG-Intron

4 enrolled 9 charts

Cholangiocarcinoma

NCT03267940 2020-02-07

Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma

Phase 1 Terminated

85 enrolled 17 charts

Cholangiocarcinoma

NCT02082522 2019-08-28

Efficacy and Safety Study of PDT Using Photofrin in Unresectable Advanced Perihilar Cholangiocarcinoma (OPUS)

28 enrolled 24 charts

Bile Duct Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT02200042 2019-08-28

Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer

1 enrolled 5 charts

Cholangiocarcinoma

NCT02254681 2018-10-03

Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC

6 enrolled 12 charts

Cholangiocarcinoma

NCT00832637 2018-06-29

Gem-ox

33 enrolled 9 charts

Bile Duct Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT00955721 2018-01-03

A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancer

9 enrolled 7 charts

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT01303159 2017-05-23

Endoscopic Bipolar Radiofrequency Probe (ENDOHPB) in the Management of Unresectable Bile Duct and Pancreatic Cancer

29 enrolled 7 charts

Pancreatic Neoplasms, Cholangiocarcinoma

NCT01543607 2017-04-24

Endoscopic Therapy of Malignant Bile Duct Strictures

1 enrolled 6 charts

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT01151761 2016-07-29

Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantation

2 enrolled 9 charts

Bile Duct Neoplasms, Gallbladder Neoplasms, Liver Neoplasms, Cholangiocarcinoma

NCT00983541 2015-08-19

Chemoradiation +Gemcitabine +Continuous 5-FU (Fluorouracil) Followed by High Dose Brachytherapy/Stereotactic Radiation Boost in Locally Advanced Intra/Extrahepatic Cholangiocarcinoma

1 enrolled 4 charts

Liver Neoplasms, Neoplasms, Cholangiocarcinoma

NCT00708877 2013-07-30

Liver Transplantation for Cholangiocarcinoma

5 enrolled 4 charts