Clinical Trials Browser

Phase 3 × Interventional × Cholangiocarcinoma × Clear all

NCT04924062 2026-04-15

KEYNOTE-966

Phase 3 Completed

158 enrolled 19 charts

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Bile Duct Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT06622057 2026-04-14

D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

Phase 3 Not yet recruiting

Gastrointestinal

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT07265674 2026-04-09

Beacon-BTC

Phase 3 Recruiting

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT04003636 2026-03-24

KEYNOTE-966

Phase 3 Completed

1,069 enrolled 19 charts 2 FDA

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Bile Duct Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT06282575 2026-03-24

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Phase 3 Recruiting

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT06109779 2026-03-04

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

Phase 3 Active not recruiting

Gastrointestinal

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT05876754 2026-02-19

ProvIDHe

Phase 3 Recruiting

Gastrointestinal

Cholangiocarcinoma

NCT03768414 2026-01-12

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

Phase 3 Completed

452 enrolled 17 charts

Gastrointestinal

Gallbladder Neoplasms, Cholangiocarcinoma

NCT07328919 2026-01-09

Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations

Phase 3 Not yet recruiting

Gastrointestinal

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT04157985 2025-12-11

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

Phase 3 Completed

DermatologicGastrointestinalGenitourinaryGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Cholangiocarcinoma

NCT07155525 2025-09-18

NBCA-MS

Phase 3 Recruiting

Gastrointestinal

Bile Duct Neoplasms, Duodenal Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma

NCT03656536 2025-08-24

FIGHT-302

Phase 3 Terminated

Gastrointestinal

Cholangiocarcinoma

NCT05342194 2025-04-23

Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study

Phase 3 Recruiting

Gastrointestinal

Cholangiocarcinoma

NCT02170090 2025-03-30

ACTICCA-1

Phase 3 Active not recruiting

Gastrointestinal

Gallbladder Neoplasms, Cholangiocarcinoma

NCT02989857 2024-08-20

ClarIDHy

Phase 3 Completed

187 enrolled 34 charts 2 FDA

Gastrointestinal

Cholangiocarcinoma

NCT05948475 2024-06-24

FIRST-308

Phase 3 Recruiting

Gastrointestinal

Cholangiocarcinoma

NCT03773302 2024-05-08

Phase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/Translocations

Phase 3 Terminated

48 enrolled 26 charts

Gastrointestinal

Cholangiocarcinoma

NCT04163900 2023-05-24

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Phase 3 Terminated

773 enrolled 15 charts

Gastrointestinal

Adenocarcinoma, Biliary Tract Neoplasms, Digestive System Neoplasms, Neoplasm Metastasis, Neoplasms, Cholangiocarcinoma

NCT02773485 2022-10-21

Chemo Alone or in Combination With Radiation in Unresectable Cholangiocarcinoma

Phase 3 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT04961970 2021-07-14

HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICC

Phase 3 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT01926236 2020-01-28

ABC06

Phase 3 Completed

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT03771846 2019-12-05

HAIC Versus Systemic Chemotherapy for Unresectable ICC

Phase 3 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT02082522 2019-08-28

Efficacy and Safety Study of PDT Using Photofrin in Unresectable Advanced Perihilar Cholangiocarcinoma (OPUS)

Phase 3 Terminated

28 enrolled 24 charts

Gastrointestinal

Bile Duct Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT02200042 2019-08-28

Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer

Phase 3 Terminated

1 enrolled 5 charts

Gastrointestinal

Cholangiocarcinoma

NCT01470443 2019-05-21

Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma

Phase 3 Unknown

Gastrointestinal

Neoplasms, Cholangiocarcinoma

NCT02232490 2019-02-26

Hepko-V5

Phase 3 Unknown

Gastrointestinal

Fibrosis, Hepatitis, Carcinoma, Hepatocellular, Liver Neoplasms, Cholangiocarcinoma

NCT03779035 2018-12-19

AdBTC-1

Phase 3 Unknown

Gastrointestinal

Gallbladder Neoplasms, Cholangiocarcinoma

NCT03081039 2018-02-19

A Study of Cisplatin or Carboplatin With Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Patients With Resected or Ablation Intra-Hepatic Cholangiocarcinoma

Phase 3 Withdrawn

Gastrointestinal

Cholangiocarcinoma

NCT03345303 2017-11-17

Bortezomib in Intrahepatic Cholangiocellular Carcinoma

Phase 3 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT02798510 2016-06-22

Clinical Trial of Adjuvant Chemotherapy Followed by Concurrent Chemoradiotherapy Compared With Adjuvant Chemotherapy Alone in Patients With Gallbladder Carcinoma and Extrahepatic Cholangiocarcinoma

Phase 3 Unknown

Gastrointestinal

Gallbladder Neoplasms, Cholangiocarcinoma

NCT02548195 2015-09-14

Oxaliplatin+Gemcitabine vs Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma

Phase 3 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT00907413 2015-06-03

PDT

Phase 3 Terminated

Gastrointestinal

Neoplasms, Cholangiocarcinoma

NCT00869635 2014-02-06

S-1 and Photodynamic Therapy in Cholangiocarcinoma

Phase 3 Completed

Gastrointestinal

Cholangiocarcinoma

NCT00653978 2011-06-22

Unilateral Versus Bilateral Stents for Bismuth Type II and III Malignant Hilar Strictures

Phase 3 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT00540735 2010-02-04

CK/PDT

Phase 3 Terminated

Gastrointestinal

Cholangiocarcinoma

NCT00090025 2009-01-14

XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary Tumors

Phase 3 Terminated

Gastrointestinal

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma