Clinical Trials

24 enrolled

Cholangiocarcinoma

NCT07476651 2026-04-16

LASER

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT07458347 2026-04-15

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

GastrointestinalGynecologicThoracic

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06728410 2026-04-08

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

38 enrolled

Cholangiocarcinoma

NCT06910722 2026-04-06

RIS-TH

36 enrolled

Cholangiocarcinoma

NCT06342414 2026-04-03

ELUCIDATE

400 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Cholangiocarcinoma

NCT04891289 2026-04-01

Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery

164 enrolled

Cholangiocarcinoma

NCT07260175 2026-03-23

adIVO

40 enrolled

Cholangiocarcinoma

NCT06140134 2026-03-20

Liver Transplantation in Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma

NCT06648057 2026-03-18

Investigation of Predictive Biomarkers in Patients With Advanced BTC Treated With Lenvatinib Plus Pembrolizumab

100 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT05285358 2026-03-13

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

12 enrolled

Gallbladder Neoplasms, Cholangiocarcinoma

NCT02379377 2026-03-09

18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant

110 enrolled

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT04792463 2026-03-09

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

500 enrolled

Uveal Melanoma, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Cholangiocarcinoma

NCT06859684 2026-03-09

HAIC-quad

25 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT07282912 2026-03-04

OLIGOMETS

54 enrolled

Adenocarcinoma Of Esophagus, Cholangiocarcinoma

NCT03942328 2026-02-24

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Phase 1/2 Recruiting

85 enrolled

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT05497531 2026-02-24

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

15 enrolled

Carcinoma, Hepatocellular, Pancreatic Neoplasms, Cholangiocarcinoma

NCT07146646 2026-02-19

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

27 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT03445585 2026-02-17

Biobank for Cholestatic Liver Diseases.

9,150 enrolled

Liver Cirrhosis, Biliary, Liver Neoplasms, Cholangitis, Sclerosing, Cholangiocarcinoma

NCT04753996 2026-02-17

Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients

300 enrolled

Cholangitis, Sclerosing, Cholangiocarcinoma

NCT07223307 2026-02-09

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

62 enrolled

Liver Neoplasms, Cholangiocarcinoma

NCT07201519 2026-02-04

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

80 enrolled

Cholangiocarcinoma

NCT06313203 2026-02-02

TOMCAT

39 enrolled

Cholangiocarcinoma

NCT06048133 2026-01-23

Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)

33 enrolled

Bile Duct Neoplasms, Cholangiocarcinoma

NCT07359586 2026-01-22

Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia

GastrointestinalHead & NeckThoracic

1,200 enrolled

Carcinoma, Hepatocellular, Hoarseness, Lung Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma

NCT06302621 2026-01-15

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

70 enrolled

Neoplasm Metastasis, Cholangiocarcinoma

NCT07235007 2026-01-13

BRAVE

120 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT07337850 2026-01-13

FAPi-2

60 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT07291063 2025-12-18

Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA

50 enrolled

Cholangiocarcinoma

NCT07291947 2025-12-18

PULSAR Combined With Immunotherapy and Chemotherapy

Phase 1/2 Recruiting

60 enrolled

Cholangiocarcinoma

NCT06416397 2025-12-16

PROTEOBILE

200 enrolled

Disease, Neoplasms, Cholangiocarcinoma

NCT03823144 2025-12-11

Intravital Microscopy in Human Solid Tumors

BreastCNSGastrointestinalSarcoma

85 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06546969 2025-12-10

Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer

15 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT06735560 2025-12-08

ELEGANCE

EndocrineGastrointestinalNET

60 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Carcinoma, Hepatocellular, Cholangiocarcinoma, Neuroendocrine Tumors

NCT06851663 2025-12-08

Trop2-targeted immunoPET Imaging of Solid Tumors

Phase 2/3 Recruiting

400 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Nasopharyngeal Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07263217 2025-12-04

Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury

Cholangiocarcinoma

NCT06440993 2025-12-01

Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

42 enrolled

Cholangiocarcinoma

NCT06925516 2025-11-28

ACADEMY

38 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT07224750 2025-11-26

MiGIC

1,000 enrolled

Esophageal Squamous Cell Carcinoma, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Stomach Neoplasms, Cholangiocarcinoma

NCT07106827 2025-11-24

A Study of GV20-0251 in Advanced or Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

10 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Testicular Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06529718 2025-11-17

SEVILLA

72 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT06058663 2025-10-20

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

16 enrolled

Cholangiocarcinoma

NCT07155525 2025-09-18

NBCA-MS

Phase 3 Recruiting

194 enrolled

Bile Duct Neoplasms, Duodenal Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma

NCT07176962 2025-09-16

A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening

1,800 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Disease, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT07070700 2025-08-12

CASTLE-ZS-02

56 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT07118176 2025-08-12

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETSarcomaThoracic

Adrenal Gland Neoplasms, Anus Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Colorectal Neoplasms, Carcinoma, Medullary, Cholangiocarcinoma, Neuroendocrine Tumors, Solitary Fibrous Tumors

NCT07105852 2025-08-06

Exploring the Safety and Efficacy of Sacituzumab Tirumotecan Combined With Pucotenlimab in the Treatment of Advanced Cholangiocarcinoma

59 enrolled

Cholangiocarcinoma

NCT06541652 2025-08-05

FFCD-2205

150 enrolled