Clinical Trials

16 enrolled

Cholangiocarcinoma

NCT06735560 2026-05-13

ELEGANCE

EndocrineGastrointestinalNET

60 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Carcinoma, Hepatocellular, Cholangiocarcinoma, Neuroendocrine Tumors

NCT07458347 2026-05-12

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

GastrointestinalGynecologicThoracic

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06728410 2026-05-08

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

38 enrolled

Cholangiocarcinoma

NCT07570849 2026-05-06

Chidamide Combined With Chemotherapy and Immunotherapy as First-line Treatment for Advanced Intrahepatic Cholangiocarcinoma

35 enrolled

Cholangiocarcinoma

NCT07030140 2026-05-01

Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma

38 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT07561775 2026-05-01

Adebrelimab Plus S-1 for Resected Cholangiocarcinoma

40 enrolled

Phase 1 Active not recruiting

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT02626312 2026-04-30

Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

36 enrolled

Fibrosis, Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT07478523 2026-04-30

FAPDIG

120 enrolled

Phase NA Not yet recruiting

Cholangiocarcinoma

NCT07558304 2026-04-30

SMART-B

84 enrolled

Phase EARLY_PHASE1 Active not recruiting

Bile Duct Neoplasms, Cholangiocarcinoma

NCT00737399 2026-04-27

Anxiety and Depression Levels in Cancer Patients After Self-Application of EFT (Emotional Freedom Techniques)

14 enrolled

Anxiety Disorders, Depression, Sleep Initiation and Maintenance Disorders, Neoplasms, Pain, Cholangiocarcinoma

NCT04891289 2026-04-22

Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery

164 enrolled

Cholangiocarcinoma

NCT05655949 2026-04-22

Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio

30 enrolled

Bile Duct Neoplasms, Cholangiocarcinoma

NCT03942328 2026-04-20

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Phase 1/2 Recruiting

85 enrolled

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT05967182 2026-04-16

A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma

24 enrolled

Cholangiocarcinoma

NCT07476651 2026-04-16

LASER

30 enrolled

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT02872831 2026-04-13

Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle

Phase NA Withdrawn

Lymphadenopathy, Pancreatic Neoplasms, Cholangiocarcinoma

NCT04834674 2026-04-07

DEB-TACE Combined With Apatinib and PD-1 for the Treatment of Intrahepatic Cholangiocarcinoma

20 enrolled

Cholangiocarcinoma

NCT07514533 2026-04-07

The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma

60 enrolled

Cholangiocarcinoma

NCT06910722 2026-04-06

RIS-TH

36 enrolled

Phase 2 Active not recruiting

Cholangiocarcinoma

NCT06178445 2026-03-27

TRAP-BTC

24 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT07260175 2026-03-23

adIVO

40 enrolled

Cholangiocarcinoma

NCT04301778 2026-03-13

Durvalumab and SNDX-6532 Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcinoma

5 enrolled 13 charts

Cholangiocarcinoma

NCT05285358 2026-03-13

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

12 enrolled

Gallbladder Neoplasms, Cholangiocarcinoma

NCT02379377 2026-03-09

18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant

110 enrolled

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT06859684 2026-03-09

HAIC-quad

25 enrolled

Phase 1 Active not recruiting

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT04708067 2026-03-05

Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma

2 enrolled

Cholangiocarcinoma

NCT07282912 2026-03-04

OLIGOMETS

54 enrolled

Adenocarcinoma Of Esophagus, Cholangiocarcinoma

NCT07432568 2026-02-25

A Study of Liposomal Irinotecan Plus 5-FU/LV HAIC With Lenvatinib and a PD-1 Inhibitor in Advanced ICC

30 enrolled

Cholangiocarcinoma

NCT04233567 2026-02-24

Infigratinib for the Treatment of Advanced or Metastatic Solid Tumors in Patients With FGFR Gene Mutations

17 enrolled 12 charts

Neoplasm Metastasis, Cholangiocarcinoma

NCT05497531 2026-02-24

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

15 enrolled

Phase 2 Active not recruiting

Carcinoma, Hepatocellular, Pancreatic Neoplasms, Cholangiocarcinoma

NCT06178588 2026-02-24

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

15 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT07146646 2026-02-19

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

27 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT07223307 2026-02-09

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

62 enrolled

Liver Neoplasms, Cholangiocarcinoma

NCT03693807 2026-02-06

A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma

35 enrolled 14 charts

Phase 1 Active not recruiting

Colorectal Neoplasms, Cholangiocarcinoma

NCT04459273 2026-02-05

FAPI PET RDRC

26 enrolled

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasm

Adrenal Gland Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Unknown Primary, Skin Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma, Neuroendocrine Tumors, Hematologic Neoplasms

NCT07201519 2026-02-04

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

80 enrolled

Cholangiocarcinoma

NCT06313203 2026-02-02

TOMCAT

39 enrolled

Cholangiocarcinoma

NCT06739252 2026-01-28

Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA

Phase 2 Terminated

1 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma, Klatskin Tumor

NCT06048133 2026-01-23

Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)

33 enrolled

Bile Duct Neoplasms, Cholangiocarcinoma

NCT07353827 2026-01-20

FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma

36 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT07235007 2026-01-13

BRAVE

120 enrolled