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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Leukemia, Myeloid, Acute 176Leukemia 148Myelodysplastic Syndromes 140Precursor Cell Lymphoblastic Leukemia-Lymphoma 113Lymphoma 101Lymphoma, Non-Hodgkin 87Multiple Myeloma 83Hodgkin Disease 75Leukemia, Lymphocytic, Chronic, B-Cell 70Congenital Abnormalities 63Leukemia, Myeloid, Chronic-Phase 60Myeloproliferative Disorders 57Lymphoma, Large B-Cell, Diffuse 57Neoplasms, Plasma Cell 54Leukemia, Myelomonocytic, Chronic 53Leukemia, Myeloid, Accelerated Phase 53Lymphoma, Follicular 52Lymphoma, Mantle-Cell 48Burkitt Lymphoma 47Lymphoma, B-Cell, Marginal Zone 45Leukemia, Myelogenous, Chronic, BCR-ABL Positive 45Lymphoma, Large-Cell, Immunoblastic 44Blast Crisis 44Anemia, Refractory, with Excess of Blasts 43Primary Myelofibrosis 40Recurrence 37Hematologic Neoplasms 35Graft vs Host Disease 35Myelodysplastic-Myeloproliferative Diseases 34Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 32

Interventions

Temozolomide 13Carboplatin 12Filgrastim 9Cyclophosphamide 9Vincristine 8Etoposide 8Peripheral Blood Stem Cell Transplantation 7Cisplatin 7Radiotherapy 6Methotrexate 5Magnetic Resonance Spectroscopy 4Thiotepa 3O(6)-benzylguanine 3Irinotecan 3Granulocyte Colony-Stimulating Factor 3Donepezil 3etoposide phosphate 2Vorinostat 2Topotecan 2Psychiatric Rehabilitation 2Paclitaxel 2Leucovorin 2Gadolinium DTPA 2Erlotinib Hydrochloride 2Cyproheptadine 2Carmustine 2Bortezomib 2Amplified Fragment Length Polymorphism Analysis 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Choroid Plexus Neoplasms × Busulfan × Clear all
NCT00006246 2009-10-07

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Pediatric Brain Tumor Consortium

Phase 1 Completed
28 enrolled
CNSLymphoidOther hematologic neoplasmOther solid neoplasmSarcoma

Familial ependymoma, Astrocytoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Recurrence, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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