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Phase

Phase 1 1

Status

Withdrawn 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 13Pancreatic Neoplasms 10Neoplasms 9Ovarian Neoplasms 8Neoplasm Metastasis 8Squamous Cell Carcinoma of Head and Neck 6Leukemia, Myeloid, Acute 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Lung Neoplasms 5Leukemia 5Glioblastoma 5Colorectal Neoplasms 5Stomach Neoplasms 4Neuroblastoma 4Lymphoma, Non-Hodgkin 4Lymphoma 4Head and Neck Neoplasms 4Fallopian Tube Neoplasms 4Central Nervous System Neoplasms 4Carcinoma, Ovarian Epithelial 4Brain Neoplasms 4Recurrence 3Gliosarcoma 3Esophageal Neoplasms 3Breast Neoplasms 3Astrocytoma 3Advanced Solid Tumors 3Unspecified Adult Solid Tumor, Protocol Specific 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Mesothelioma, Malignant 2

Interventions

Temozolomide 8Filgrastim 5Carboplatin 5Peripheral Blood Stem Cell Transplantation 3O(6)-benzylguanine 3Etoposide 3Vorinostat 2Vincristine 2Granulocyte Colony-Stimulating Factor 2Cyclophosphamide 2Bortezomib 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2veliparib 1temsirolimus 1romidepsin 1palbociclib 1lonafarnib 1laromustine 1ixabepilone 1ispinesib 1exatecan 1etoposide phosphate 1entinostat 1carboxyamido-triazole 1azurin (50-77) 1Verteporfin 1Topotecan 1Thiotepa 1Thalidomide 1Surgical Procedures, Operative 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Choroid Plexus Neoplasms × Drug Therapy × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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