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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Breast Neoplasms 5Glioblastoma 4Oligodendroglioma 3Gliosarcoma 3Glioma 3Brain Neoplasms 3Astrocytoma 3Prostatic Neoplasms 2Neoplasm Metastasis 2Lung Neoplasms 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Head and Neck Neoplasms 2Colorectal Neoplasms 2Central Nervous System Neoplasms 2Urinary Bladder Neoplasms 1Urethral Neoplasms 1Supratentorial Neoplasms 1Stomach Neoplasms 1Spinal Cord Neoplasms 1Sarcoma 1Rhabdoid Tumor 1Rectal Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Optic Nerve Glioma 1Myelodysplastic Syndromes 1Medulloblastoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1

Interventions

Temozolomide 13Carboplatin 12Filgrastim 9Cyclophosphamide 9Vincristine 8Etoposide 8Peripheral Blood Stem Cell Transplantation 7Cisplatin 7Radiotherapy 6Methotrexate 5Magnetic Resonance Spectroscopy 4Thiotepa 3O(6)-benzylguanine 3Irinotecan 3Granulocyte Colony-Stimulating Factor 3Donepezil 3etoposide phosphate 2Vorinostat 2Topotecan 2Paclitaxel 2Leucovorin 2Gadolinium DTPA 2Erlotinib Hydrochloride 2Cyproheptadine 2Carmustine 2Bortezomib 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2veliparib 1temsirolimus 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Choroid Plexus Neoplasms × lonafarnib × Clear all
NCT00015899 2009-10-14

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Pediatric Brain Tumor Consortium

Phase 1 Completed
53 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

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