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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Breast Neoplasms 10Ovarian Neoplasms 9Fallopian Tube Neoplasms 8Triple Negative Breast Neoplasms 7Pancreatic Neoplasms 5Neoplasms 4Astrocytoma 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasm Metastasis 3Lymphoma 3Leukemia, Myelomonocytic, Chronic 3Leukemia, Myeloid, Acute 3Glioblastoma 3Uterine Cervical Neoplasms 2Thrombocythemia, Essential 2Small Cell Lung Carcinoma 2Rectal Neoplasms 2Prostatic Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Polycythemia Vera 2Medulloblastoma 2Lymphoma, Follicular 2Leukemia, Myelomonocytic, Acute 2Leukemia, Lymphocytic, Chronic, B-Cell 2Hereditary Breast and Ovarian Cancer Syndrome 2Gliosarcoma 2Carcinoma, Non-Small-Cell Lung 2Burkitt Lymphoma 2Breast Neoplasms, Male 2Brain Neoplasms 2

Interventions

Temozolomide 7Radiotherapy 3O(6)-benzylguanine 3Carboplatin 3Vorinostat 2Vincristine 2Methotrexate 2Magnetic Resonance Spectroscopy 2Cyclophosphamide 2Cisplatin 2Amplified Fragment Length Polymorphism Analysis 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2veliparib 1romidepsin 1ixabepilone 1ispinesib 1entinostat 1carboxyamido-triazole 1becatecarin 1Verteporfin 1Thiotepa 1Surgical Procedures, Operative 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Peripheral Blood Stem Cell Transplantation 1Paclitaxel 1PT-100 dipeptide 1Nivolumab 1Lenalidomide 1Granulocyte Colony-Stimulating Factor 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Choroid Plexus Neoplasms × veliparib × Clear all
NCT00946335 2014-07-09

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
31 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

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