Clinical Trials Browser

Phase 2 × Interventional × Clear-cell metastatic renal cell carcinoma × Clear all

NCT06783348 2026-06-04

RENALUT

Phase 2 Recruiting

Clear-cell metastatic renal cell carcinoma, Kidney Neoplasms

NCT05263050 2026-05-22

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

Phase 2 Recruiting

EndocrineGenitourinaryNET

Clear-cell metastatic renal cell carcinoma, Carcinoid Tumor, Carcinoma, Renal Cell, Neuroendocrine Tumors

NCT07578025 2026-05-11

Zanzalintinib and MO-03 for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07576725 2026-05-08

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

Phase 2 Not yet recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

Clear-cell metastatic renal cell carcinoma, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Hodgkin Disease, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Kaposi, Colorectal Neoplasms, Carcinoma, Merkel Cell

NCT07043608 2026-05-01

ZAMBONI

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT05361720 2026-04-27

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Phase 2 Recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07510334 2026-04-03

VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07488572 2026-03-23

Safety and Efficacy of Yiwoxidan Anti (AK112) Monotherapy in Patients With Metastatic Renal Clear Cell Carcinoma Who Are Intolerant to TKI Treatment: a Prospective, Single Arm, Phase II Clinical Study

Phase 2 Enrolling by invitation

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT04904302 2026-03-20

Sitravatinib and Nivolumab for the Treatment of Metastatic or Advanced Clear Cell Renal Cell Cancer

Phase 2 Terminated

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT05012371 2026-03-05

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

Phase 2 Active not recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT04370509 2025-11-19

Pembrolizumab With or Without Axitinib for Clear Cell Kidney Cancer in Patients Undergoing Surgery

Phase 2 Terminated

6 enrolled 11 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07218692 2025-10-20

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT01693822 2024-11-21

A-PREDICT

Phase 2 Completed

65 enrolled 15 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT02978404 2024-06-28

Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases

Phase 2 Completed

CNSDermatologicGenitourinaryThoracic

Clear-cell metastatic renal cell carcinoma, Brain Neoplasms, Melanoma, Small Cell Lung Carcinoma

NCT05567588 2024-02-01

Pembrolizumab Plus Radiotherapy for Advanced Renal Cancer

Phase 2 Unknown

Clear-cell metastatic renal cell carcinoma

NCT05879471 2023-07-24

68Ga-NY104 PET/CT in Patients With Metastatic Clear Cell Renal Cell Carcinoma

Phase 2 Unknown

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT03679767 2023-07-21

A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Phase 2 Completed

121 enrolled 25 charts

DermatologicGenitourinaryThoracic

Clear-cell metastatic renal cell carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma

NCT02917772 2022-10-06

TITAN-RCC

Phase 2 Completed

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT03334409 2022-03-31

Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery

Phase 2 Terminated

5 enrolled 16 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT01896271 2021-08-23

High Dose IL-2 and Stereotactic Ablative Body Radiation Therapy for Metastatic Renal Cancer

Phase 2 Completed

30 enrolled 12 charts

Clear-cell metastatic renal cell carcinoma, Kidney Neoplasms, Neoplasm Metastasis

NCT02960906 2021-04-26

BIONIKK

Phase 2 Completed

Clear-cell metastatic renal cell carcinoma

NCT02019576 2021-03-23

Stereotactic Radiotherapy for Metastatic Kidney Cancer Being Treated With Sunitinib

Phase 2 Completed

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT01391130 2019-07-23

A Study of LY2510924 and Sunitinib in Patients With Metastatic Renal Cell Carcinoma

Phase 2 Terminated

110 enrolled 14 charts

Clear-cell metastatic renal cell carcinoma, Neoplasm Metastasis, Neoplasms

NCT01499121 2018-03-06

Study of Efficacy and Safety of Sunitinib Given on an Individualized Schedule

Phase 2 Completed

Clear-cell metastatic renal cell carcinoma

NCT01715935 2016-08-19

NEORAD

Phase 2 Completed

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT02002312 2015-08-13

Phase II Study of Lutetium-177 Labeled Girentuximab in Patients With Advanced Renal Cancer

Phase 2 Completed

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell