Announcements Trials
Browse Landscape

Phase

Phase 1/2 2

Status

Terminated 1Completed 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2

Conditions

Melanoma 20Neoplasm Metastasis 8Leukemia, Myeloid, Acute 7Skin Neoplasms 6Ovarian Neoplasms 6Lymphoma, Non-Hodgkin 6Colorectal Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Leukemia, Lymphocytic, Chronic, B-Cell 5Uveal Melanoma 4Stomach Neoplasms 4Squamous Cell Carcinoma of Head and Neck 4Neoplasms 4Triple Negative Breast Neoplasms 3Recurrence 3Rectal Neoplasms 3Pancreatic Neoplasms 3Mesothelioma, Malignant 3Lymphoma, Follicular 3Lymphoma 3Lung Neoplasms 3Leukemia 3Esophageal Neoplasms 3Carcinoma, Renal Cell 3Uterine Cervical Neoplasms 2Sarcoma 2Pleural Effusion, Malignant 2Neuroblastoma 2Myelodysplastic Syndromes 2Multiple Myeloma 2

Interventions

Oxaliplatin 27Fluorouracil 23Leucovorin 22Cetuximab 22Bevacizumab 21Nivolumab 16Capecitabine 16Irinotecan 15pembrolizumab 11Magnetic Resonance Spectroscopy 11Specimen Handling 10encorafenib 8Folfox protocol 7trifluridine tipiracil drug combination 6Ipilimumab 6Exercise 6fludarabine 5cemiplimab 5Trastuzumab 5Gemcitabine 5Cyclophosphamide 5Cisplatin 5Blood Specimen Collection 5Biopsy 5regorafenib 4pertuzumab 4adagrasib 4Trifluridine 4Pemetrexed 4Immune Checkpoint Inhibitors 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Colonic Neoplasms × Interleukin-2 × 1 year × Clear all
NCT03745326 2026-05-19

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
5 enrolled 14 charts
Gastrointestinal

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

Intima Bioscience, Inc.

Phase 1/2 Completed
23 enrolled
Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

Data powered by HemOnc (CC BY 4.0) Colophon âš¡