Announcements Trials
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Phase

Phase 1/2 3

Status

Terminated 1Recruiting 1Completed 1

Sponsor Class

NIH 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 3

Conditions

Melanoma 15Neoplasm Metastasis 11Ovarian Neoplasms 9Pancreatic Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Stomach Neoplasms 6Skin Neoplasms 6Leukemia, Myeloid, Acute 6Colorectal Neoplasms 6Carcinoma, Renal Cell 6Triple Negative Breast Neoplasms 4Gastrointestinal Neoplasms 4Breast Neoplasms 4Vulvar Neoplasms 3Uterine Cervical Neoplasms 3Urogenital Neoplasms 3Rectal Neoplasms 3Neuroblastoma 3Myelodysplastic Syndromes 3Multiple Myeloma 3Leukemia 3Colonic Neoplasms 3Vaginal Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pleural Effusion, Malignant 2Penile Neoplasms 2Oropharyngeal Neoplasms 2Neoplasms 2

Interventions

Oxaliplatin 27Fluorouracil 23Leucovorin 22Cetuximab 22Bevacizumab 21Nivolumab 16Capecitabine 16Irinotecan 15pembrolizumab 11Magnetic Resonance Spectroscopy 11Specimen Handling 10encorafenib 8Folfox protocol 7trifluridine tipiracil drug combination 6Ipilimumab 6Exercise 6fludarabine 5cemiplimab 5Trastuzumab 5Gemcitabine 5Cyclophosphamide 5Cisplatin 5Blood Specimen Collection 5Biopsy 5regorafenib 4pertuzumab 4adagrasib 4Trifluridine 4Pemetrexed 4Immune Checkpoint Inhibitors 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Colonic Neoplasms × aldesleukin × 1 year × Clear all
NCT03190941 2026-05-29

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
110 enrolled
Gastrointestinal

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT03745326 2026-05-19

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
5 enrolled 14 charts
Gastrointestinal

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

Intima Bioscience, Inc.

Phase 1/2 Completed
23 enrolled
Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

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