Clinical Trials Browser

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT06949111 2025-07-01

Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）

Phase 2 Recruiting

128 enrolled

Gastrointestinal

Colonic Neoplasms

NCT05870800 2025-05-25

NICER

Phase 2 Recruiting

28 enrolled

Gastrointestinal

Colonic Neoplasms

NCT04068103 2025-05-07

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

Phase 2/3 Active not recruiting

635 enrolled 9 charts

Gastrointestinal

Colonic Neoplasms

NCT06790212 2025-03-17

Neoadjuvant CAPOX Plus Ivonescimab Versus CAPOX for Locally Advanced Colon Cancer

Phase 2 Not yet recruiting

168 enrolled

Gastrointestinal

Colonic Neoplasms

NCT01167725 2024-12-27

Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer

Phase 3 Terminated

340 enrolled

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT04534218 2024-12-20

REPROGRAM-01

Phase 2 Completed

49 enrolled

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis

NCT02861300 2024-12-19

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

Phase 1/2 Completed

50 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Rectal Neoplasms, Colorectal Neoplasms

NCT04488159 2024-09-20

iMAGINE

Phase 3 Withdrawn

Gastrointestinal

Colonic Neoplasms, Motor Activity

NCT02355379 2024-07-08

ADAGE

Phase 3 Recruiting

774 enrolled

Gastrointestinal

Colonic Neoplasms

NCT03854799 2023-10-19

AVANA

Phase 2 Completed

101 enrolled

Gastrointestinal

Colonic Neoplasms

NCT00958737 2023-09-29

IDEA

Phase 3 Unknown

2,000 enrolled

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT04259944 2023-09-28

Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial

Phase 2 Unknown

140 enrolled

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT05914389 2023-08-08

ICONIC

Phase 2 Recruiting

100 enrolled

Gastrointestinal

Colonic Neoplasms

NCT00107250 2023-08-04

AZD2171 + Chemotherapy in Advanced NSCLC, Colorectal Cancer, or Other Cancer Suitable for Treatment With Capecitabine (Non-Small Lung Cancer Patients Closed to Enrollment as 8/9/07)

Phase 1 Completed

50 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03775525 2022-12-23

GEN602

Phase 1 Unknown

127 enrolled

BreastDermatologicGastrointestinalHead & NeckLymphoidSarcoma

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Basal Cell, Colonic Neoplasms, Lymphoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Lymphoma, T-Cell, Cutaneous

NCT00314353 2021-10-06

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

Phase 2 Terminated

7 enrolled 5 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00070213 2021-09-27

Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Completed

460 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00640081 2021-09-22

Combination Chemotherapy and Cetuximab as First-Line Therapy in Treating Patients With Advanced and/or Metastatic Colorectal Cancer

Phase 2 Completed

169 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02393755 2021-07-08

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Phase 1/2 Completed

42 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT01280643 2021-03-15

Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Phase NA Terminated

3 enrolled 8 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00104689 2021-02-21

Capecitabine and Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Phase 2 Completed

60 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00423696 2021-02-17

Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

Phase 2 Completed

145 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04089631 2020-08-06

CIRCULATE

Phase 3 Recruiting

4,812 enrolled

Gastrointestinal

Colonic Neoplasms

NCT01471353 2020-07-23

SorCape

Phase 2 Completed

43 enrolled 12 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT00004187 2019-06-26

Capecitabine and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Phase 1/2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00647530 2019-05-17

FOxTROT

Phase 2/3 Unknown

1,053 enrolled

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00003867 2018-09-10

Irinotecan and Capecitabine in Treating Patients With Solid Tumors

Phase 1 Completed

30 enrolled

BreastGastrointestinal

Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT02216149 2018-08-28

FluoHeart

Phase 2 Terminated

20 enrolled

Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00749450 2018-07-27

Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer

Phase 3 Completed

6,088 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01048580 2018-06-28

Study of Perifosine + Capecitabine for Colon Cancer Patients

Phase 1 Completed

10 enrolled

Gastrointestinal

Colonic Neoplasms

NCT00398879 2018-03-14

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

Phase 2 Completed

381 enrolled

Gastrointestinal

Colonic Neoplasms

NCT03435666 2018-02-19

Capecitabine

Phase 1 Unknown

45 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms

NCT01729923 2018-01-16

ADAPT

Phase 2 Terminated

27 enrolled 10 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00226941 2017-12-08

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Phase 1/2 Terminated

23 enrolled 18 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT01279681 2017-12-08

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Phase 3 Terminated

32 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

Clinical Trials

OPTICAL

Neoadjuvant Iparomlimab/Tuvonralimab Plus CAPEOX Versus Iparomlimab/Tuvonralimab Plus CAPEOX and Propranolol for Locally Advanced pMMR Colon Cancer: A Prospective, Single-Center, Multi-Cohort Study

Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma

COLOCROSS

TRIUNITE-08

Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer

CHIMERA

ERASE-CRC

A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer

Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer

NeoCHIC

ACE

The Sagittarius Trial

Neoadjuvant CAPOX Plus Tislelizumab vs CAPOX in MSS High-Risk Locally Advanced Colon Cancer

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）

NICER

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

Neoadjuvant CAPOX Plus Ivonescimab Versus CAPOX for Locally Advanced Colon Cancer

Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer

REPROGRAM-01

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

iMAGINE

ADAGE

AVANA

IDEA

Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial

ICONIC

AZD2171 + Chemotherapy in Advanced NSCLC, Colorectal Cancer, or Other Cancer Suitable for Treatment With Capecitabine (Non-Small Lung Cancer Patients Closed to Enrollment as 8/9/07)

GEN602

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer

Combination Chemotherapy and Cetuximab as First-Line Therapy in Treating Patients With Advanced and/or Metastatic Colorectal Cancer

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Capecitabine and Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

CIRCULATE

SorCape

Capecitabine and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

FOxTROT

Irinotecan and Capecitabine in Treating Patients With Solid Tumors

FluoHeart

Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer

Study of Perifosine + Capecitabine for Colon Cancer Patients

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

Capecitabine

ADAPT

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer